CD217 (IL-17 Receptor A) Mouse anti-Human, Clone: 424LTS, Functional Grade, eBioscience™

Mouse Monoclonal Antibody, Functional Grade

Overview
Brand: Affymetrix eBioscience

Manufacturer Part Number: 16-7917-85

UNSPSC: 12352200

Code: Z2

Additional Details:
Additional Details: Weight: 0.01000kg



Disclaimers: For Research Use Only.

Product Code. 15218817

Quantity Price
1 £ 213.39 / 500µg
Estimated Shipment date
from Supplier 04-05-2017
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Description and Specification

Specification

Formulation aqueous buffer, no sodium azide
Primary or Secondary Primary
Conjugate Unlabeled
Gene Alias IL-17R, IL-17RA
Regulatory Status RUO
Isotype IgG1
Species Reactivity Human
Monoclonal or Polyclonal Monoclonal
Host Species Mouse
Applications Functional Assay
Concentration 1mg/mL
Storage Requirements Store at 2-8°C.
Quantity 500μg
Clone 424LTS
Format Purified
Antigen CD217 (IL-17 Receptor A)

The 424LTS monoclonal antibody reacts with and blocks IL-17A binding to human interleukin 17 receptor A (IL-17RA, IL-17R). IL-17RA is a type I membrane protein of approximately 96kDa (866 amino acids) and is involved in inflammatory responses to IL-17A, IL-17F and IL-17AF heterodimer. It forms heterodimeric complexes with several other members of its receptor family, including IL-17RC for IL-17A and IL-17F signaling and IL-17RC for IL-17E (IL-25) signaling. IL-17RA is ubiquitously expressed, but in leukocytes its expression is elevated on granulocytes and monocytes.