CD217 (IL-17 Receptor A) Mouse anti-Human, APC, Clone: 424LTS, eBioscience™

Mouse Monoclonal Antibody

Overview
Brand: Affymetrix eBioscience

Manufacturer Part Number: 17-7917-42

Code: NEW

Additional Details:
Additional Details: Weight: 0.23750kg



Disclaimers: For Research Use Only.

Product Code. 15528206

Quantity Price
1 £ 182.82 / 100 tests
Estimated Shipment date
from Supplier 02-05-2017
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Description and Specification

Specification

Conjugate APC
Gene Alias IL-17RA
Primary or Secondary Primary
Host Species Mouse
Quantity 100 tests
Storage Requirements Store at 2-8°C. Do not freeze. Light-sensitive material.
Concentration 5μL (0.25μg)/test
Monoclonal or Polyclonal Monoclonal
Antigen CD217 (IL-17 Receptor A)
Isotype IgG1
Clone 424LTS
Regulatory Status RUO
Format Conjugated
Formulation aqueous buffer, 0.09% sodium azide, may contain carrier protein/stabilizer
Species Reactivity Human
Applications Flow Cytometry

The 424LTS monoclonal antibody reacts with and blocks IL-17A binding to human interleukin 17 receptor A (IL-17RA, IL-17R). IL-17RA is a type I membrane protein of approximately 96kDa (866 amino acids) and is involved in inflammatory responses to IL-17A, IL-17F and IL-17AF heterodimer. It forms heterodimeric complexes with several other members of its receptor family, including IL-17RC for IL-17A and IL-17F signaling and IL-17RC for IL-17E (IL-25) signaling. IL-17RA is ubiquitously expressed, but in leukocytes its expression is elevated on granulocytes and monocytes.