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CD21/CD35, Biotin, clone: eBio8D9 (8D9), eBioscience™

Rat Monoclonal Antibody

Brand:  Affymetrix eBioscience 13-0211-82

Code : Z2

Additional Details : Weight : 0.25000kg

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Product Code. 15249489

  • £99.42 / 100µg


Estimated Shipment date
from Supplier 29-06-2018
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Description

Description

Description: The monoclonal antibody eBio8D9 reacts with an eptiope shared by mouse CD21 (CR2) and CD35 (CR1). CD21 and CD35 are alternatively spliced transcripts from the Cr2 gene, which produce cell-surface proteins of 145 and 190 kDa, respectively. CD21 and CD35 are expressed by mature B cells, but not on thymocytes, peripheral T cells, erythrocytes or platelets. Furthermore, there is some evidence which demonstrates their expression on macrophages. CD21 is a receptor for the complement component C3d and Epstein-Barr virus (EBV). In association with CD19 and CD81, CD21 also participates in B-cell activation through the B cell receptor. Cr2-deficient mice display impaired inflammatory and humoral immune responses in vivo.The anti-mouse CD21/35 monoclonal antibody clones eBio4E3 and eBio8D9 do not cross-block each other, suggesting that they bind to different epitopes.Applications Reported: This eBio8D9 (8D9) antibody has been reported for use in flow cytometric analysis.Applications Tested: This eBio8D9 (8D9) antibody has been tested by flow cytometric analysis of mouse splenocytes. This can be used at less than or equal to 0.25 μg per test. A test is defined as the amount (μg) of antibody that will stain a cell sample in a final volume of 100 μL. Cell number should be determined empirically but can range from 10^5 to 10^8 cells/test. It is recommended that the antibody be carefully titrated for optimal performance in the assay of interest.Filtration: 0.2μm post-manufacturing filtered.
Specifications

Specifications

CD21/CD35
Monoclonal
0.5mg/mL
PBS with 0.1% gelatin and 0.09% sodium azide; pH 7.2
P19070
EBV receptor, complement C3d receptor, complement receptor type 2, epstein-Barr virus receptor, C3-binding protein, C3b/C4b receptor, CD35 antigen, Knops blood group antigen, complement component receptor 1, complement receptor type 1
Rat
Affinity chromatography
RUO
Antibody
Monoclonal
Murine
Flow Cytometry
eBio8D9 (8D9)
Biotin
Cr2
Conjugated
Cr2
IgG2a, lambda
100μg
Store at 2-8°C. Do not freeze.
Primary
12902
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