CD209a (DC-SIGN) Mouse anti-Mouse, Alexa Fluor 488, Clone: MMD3, eBioscience™

Mouse Monoclonal Antibody

Overview
Brand: Affymetrix eBioscience

Manufacturer Part Number: 53-2094-80

Code: NEW

Additional Details:
Additional Details: Weight: 0.09500kg



Disclaimers: For Research Use Only.

Product Code. 15540207

Quantity Price
1 £ 73.93 / 25µg
Estimated Shipment date
from Supplier 05-05-2017
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Description and Specification

Specification

Quantity 25μg
Antigen CD209a (DC-SIGN)
Regulatory Status RUO
Concentration 0.5mg/mL
Format Conjugated
Applications Immunocytochemistry
Applications Immunohistochemistry
Applications Immunohistochemistry (Frozen)
Applications Microscopy
Isotype IgG2c
Primary or Secondary Primary
Monoclonal or Polyclonal Monoclonal
Species Reactivity Mouse
Conjugate Alexa Fluor 488
Storage Requirements Store at 2-8°C. Do not freeze. Light-sensitive material.
Clone MMD3
Formulation aqueous buffer, 0.09% sodium azide, may contain carrier protein/stabilizer
Host Species Mouse

This MMD3 monoclonal antibody recognizes mouse CD209a, which is also known as DC-SIGN. CD209a is a type II transmembrane C-type lectin expressed on a subset of dendritic cells, including some CD4+, CD8- and plasmacytoid pre-dendritic cells. Studies indicate that CD209a expression can vary according to the activation state of the host. Moreover, CD209a is down-regulated in spleen-derived dendritic cell cultures supplemented with GM-CSF. CD209a is involved in mediating the innate immune response by binding microbial carbohydrates.

Cross-blocking studies suggest that MMD3 recognizes a different a different epitope from LWC06 and 5H10.