CD209a, Alexa Fluor 488, clone: MMD3, eBioscience™
Mouse Monoclonal Antibody
Brand: Affymetrix eBioscience 53-2094-80
Code : NEW
Additional Details : Weight : 0.09500kg
DescriptionDescription: This MMD3 monoclonal antibody recognizes mouse CD209a, which is also known as DC-SIGN. CD209a is a type II transmembrane C-type lectin expressed on a subset of dendritic cells, including some CD4+, CD8- and plasmacytoid pre-dendritic cells. Studies indicate that CD209a expression can vary according to the activation state of the host. Moreover, CD209a is down-regulated in spleen-derived dendritic cell cultures supplemented with GM-CSF. CD209a is involved in mediating the innate immune response by binding microbial carbohydrates.Cross-blocking studies suggest that MMD3 recognizes a different a different epitope from LWC06 and 5H10.Applications Reported: This MMD3 antibody has been reported for use in immunohistochemical staining of frozen tissue sections, microscopy, immunohistochemical staining, and immunocytochemistry.Applications Tested: This MMD3 antibody has been tested by immunohistochemistry on frozen 5-week-old mouse thymus and can be used at less than or equal to 20 μg/mL. It is recommended that the antibody be carefully titrated for optimal performance in the assay of interest.Excitation: 488 nm; Emission: 519 nm; Laser: Blue Laser.Filtration: 0.2μm post-manufacturing filtered.
|PBS with 0.1% gelatin and 0.09% sodium azide; pH 7.2|
|CD209, CDSIGN, CIRE, DC-SIGN, DC-SIGN1, Dcsign, MGC130443, SIGN-R1, SIGNR5, CD209a|
|Alexa Fluor 488|
|Store at 2-8°C. Do not freeze. Light-sensitive material.|
For Research Use Only.