missing translation for 'onlineSavingsMsg'
Learn More

CD209 (DC-SIGN) Rat anti-Human, APC, Clone: eB-h209, eBioscience™

Rat Monoclonal Antibody

£91.25 - £197.00

Specifications

Antigen CD209 (DC-SIGN)
Clone eB-h209
Target Species Human
Conjugate APC
Isotype IgG2a, kappa
View More Specs

Products 2
Product Code Brand Quantity Price Quantity & Availability  
Product Code Brand Quantity Price Quantity & Availability  
15568056 View Documents Affymetrix eBioscience
17-2099-41
25 Tests £91.25
25 tests View alternative products
Save Up to 
»
Estimated Shipment date
from Supplier 14-05-2020
Please to purchase this item. Need a web account? Register with us today!
15578056 View Documents Affymetrix eBioscience
17-2099-42
100 Tests £197.00
100 tests View alternative products
Save Up to 
»
EU Stock 3 Please to purchase this item. Need a web account? Register with us today!
Description

Description

This gene encodes a transmembrane receptor and is often referred to as DC-SIGN because of its expression on the surface of dendritic cells and macrophages. The encoded protein is involved in the innate immune system and recognizes numerous evolutionarily divergent pathogens ranging from parasites to viruses with a large impact on public health. The protein is organized into three distinct domains: an N-terminal transmembrane domain, a tandem-repeat neck domain and C-type lectin carbohydrate recognition domain. The extracellular region consisting of the C-type lectin and neck domains has a dual function as a pathogen recognition receptor and a cell adhesion receptor by binding carbohydrate ligands on the surface of microbes and endogenous cells. The neck region is important for homo-oligomerization which allows the receptor to bind multivalent ligands with high avidity. Variations in the number of 23 amino acid repeats in the neck domain of this protein are rare but have a significant impact on ligand binding ability. This gene is closely related in terms of both sequence and function to a neighboring gene (GeneID 10332; often referred to as L-SIGN). DC-SIGN and L-SIGN differ in their ligand-binding properties and distribution. Alternative splicing results in multiple variants.
Specifications

Specifications

CD209 (DC-SIGN)
Human
IgG2a, kappa
Monoclonal
Liquid
Antibody
4° C, store in dark, DO NOT FREEZE!
eB-h209
APC
Flow Cytometry
Primary
Monoclonal
PBS with 0.1% gelatin, 0.2% BSA and 0.09% sodium azide; pH 7.2
RUO

For Research Use Only.