CD209 (DC-SIGN), CD209a Mouse anti-Mouse, eFluor 660, Clone: MMD3, eBioscience™

Mouse Monoclonal Antibody

Brand:  Affymetrix eBioscience 50-2094-80

Product Code. 15351890

Disclaimers:

For Research Use Only.

Description

This MMD3 monoclonal antibody recognizes mouse CD209a, which is also known as DC-SIGN. CD209a is a type II transmembrane C-type lectin expressed on a subset of dendritic cells, including some CD4+, CD8- and plasmacytoid pre-dendritic cells. Studies indicate that CD209a expression can vary according to the activation state of the host. Moreover, CD209a is down-regulated in spleen-derived dendritic cell cultures supplemented with GM-CSF. CD209a is involved in mediating the innate immune response by binding microbial carbohydrates.

Cross-blocking studies suggest that MMD3 recognizes a different a different epitope from LWC06 and 5H10.

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Specifications

• Antigen: CD209 (DC-SIGN), CD209a
• Clone: MMD3
• Conjugate: eFluor 660
• Formulation: aqueous buffer, 0.09% sodium azide, may contain carrier protein/stabilizer
• Isotype: IgG2c
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Target Species: Murine

• Applications: Immunohistochemistry (Frozen)
• Concentration: 0.2mg/mL
• Format: Conjugated
• Host Species: Murine
• Quantity: 25μg
• Storage Requirements: Store at 2-8°C. Do not freeze. Light-sensitive material.
• Monoclonal or Polyclonal: Monoclonal