CD209 (DC-SIGN), CD209a Mouse anti-Mouse, eFluor 660, Clone: MMD3, eBioscience™

Mouse Monoclonal Antibody

Overview
Brand: Affymetrix eBioscience

Manufacturer Part Number: 50-2094-80

UNSPSC: 12352200

Code: Z2

Additional Details:
Additional Details: Weight: 0.25000kg



Disclaimers: For Research Use Only.

Product Code. 15351890

Quantity Price
1 £ 72.77 / 25µg
Estimated Shipment date
from Supplier 04-04-2017
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Description and Specification

Specification

Conjugate eFluor 660
Clone MMD3
Formulation aqueous buffer, 0.09% sodium azide, may contain carrier protein/stabilizer
Primary or Secondary Primary
Applications Flow Cytometry
Applications Immunohistochemistry (Frozen)
Storage Requirements Store at 2-8°C. Do not freeze. Light-sensitive material.
Quantity 25μg
Regulatory Status RUO
Monoclonal or Polyclonal Monoclonal
Concentration 0.2mg/mL
Host Species Mouse
Species Reactivity Mouse
Isotype IgG2c
Format Conjugated
Antigen CD209 (DC-SIGN), CD209a

This MMD3 monoclonal antibody recognizes mouse CD209a, which is also known as DC-SIGN. CD209a is a type II transmembrane C-type lectin expressed on a subset of dendritic cells, including some CD4+, CD8- and plasmacytoid pre-dendritic cells. Studies indicate that CD209a expression can vary according to the activation state of the host. Moreover, CD209a is down-regulated in spleen-derived dendritic cell cultures supplemented with GM-CSF. CD209a is involved in mediating the innate immune response by binding microbial carbohydrates.

Cross-blocking studies suggest that MMD3 recognizes a different a different epitope from LWC06 and 5H10.