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CD206 (MMR), PerCP-eFluor™ 710, clone: 19.2, eBioscience™

Mouse Monoclonal Antibody

Brand:  Affymetrix eBioscience 46-2069-42

Code : NEW

Additional Details : Weight : 0.23750kg

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Product Code. 15579216

  • £187.12 / 100 tests


EU Stock 5
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Description

Description

Description: This 19.2 monoclonal antibody reacts with human CD206, which is also known as the macrophage mannose receptor (MMR). CD206 is expressed on macrophages and dendritic cells. This type I transmembrane protein can also be detected on non-immune cells, including hepatic and lymphathic epithelia and kidney mesengial cells. CD206 binds to glycoproteins that terminate in D-mannose, L-fucose, or N-acetylglucosamine, as well as a variety of hormones. This receptor undergoes constitutive internalization and recycling between the plasma membrane and the endosomal compartment. CD206 is involved in antigen processing and presentation, cell migration, and intracellular signaling. Moreover, CD206 plays a key role in phagocytosis pathogens such as Candida albicans, Leishmania, and Mycobacterium tuberculosis.Applications Reported: This 19.2 antibody has been reported for use in flow cytometric analysis.Applications Tested: This 19.2 antibody has been pre-titrated and tested by flow cytometric analysis of 3 day recombinant GM-CSF-cultured human peripheral blood monocytes. This can be used at 5 μL (0.06 μg) per test. A test is defined as the amount (μg) of antibody that will stain a cell sample in a final volume of 100 μL. Cell number should be determined empirically but can range from 10^5 to 10^8 cells/test. PerCP-eFluor® 710 can be used in place of PE-Cy5, PE-Cy5.5 or PerCP-Cy5.5. PerCP-eFluor® 710 emits at 710 nm and is excited with the blue laser (488 nm). Please make sure that your instrument is capable of detecting this fluorochrome. For a filter configuration, we recommend using the 685 LP dichroic mirror and 710/40 band pass filter, however the 695/40 band pass filter is an acceptable alternative. Our testing indicates that PerCP-eFluor® 710 conjugated antibodies are stable when stained samples are exposed to freshly prepared 2% formaldehyde overnight at 4°C, but please evaluate for alternative fixation protocols.Excitation: 488 nm; Emission: 710 nm; Laser: Blue Laser.Filtration: 0.2μm post-manufacturing filtered.
Specifications

Specifications

CD206 (MMR)
Monoclonal
5μl/Test
PBS with 0.1% gelatin, 0.2% BSA and 0.09% sodium azide; pH 7.2
P22897
AW259686, CD206, MR, MMR, macrophage mannose receptor 1, MRC1
Murine
Affinity chromatography
RUO
Antibody
Monoclonal
Human
Flow Cytometry
19.2
PerCP-eFluor 710
MRC1
Conjugated
MRC1
IgG1, kappa
100 Tests
Store at 2-8°C. Do not freeze. Light-sensitive material.
Primary
4360
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