CD206 (MMR) Mouse anti-Human, eFluor 450, Clone: 19.2, eBioscience™

Mouse Monoclonal Antibody

Overview
Brand: Affymetrix eBioscience

Manufacturer Part Number: 48-2069-42

Code: NEW

Additional Details:
Additional Details: Weight: 0.23750kg



Disclaimers: For Research Use Only.

Product Code. 15519736

Quantity Price
1 £ 158.36 / 100 tests
Estimated Shipment date
from Supplier 03-04-2017
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Description and Specification

Specification

Applications Flow Cytometry
Primary or Secondary Primary
Quantity 100 tests
Conjugate eFluor 450
Storage Requirements Store at 2-8°C. Do not freeze. Light-sensitive material.
Antigen CD206 (MMR)
Formulation aqueous buffer, 0.09% sodium azide, may contain carrier protein/stabilizer
Isotype IgG1
Regulatory Status RUO
Monoclonal or Polyclonal Monoclonal
Format Conjugated
Concentration 5μL (0.25μg)/test
Species Reactivity Human
Gene Alias Macrophage mannose receptor
Clone 19.2
Host Species Mouse

This 19.2 monoclonal antibody reacts with human CD206, which is also known as the macrophage mannose receptor (MMR). CD206 is expressed on macrophages and dendritic cells. This type I transmembrane protein can also be detected on non-immune cells, including hepatic and lymphathic epithelia and kidney mesengial cells. CD206 binds to glycoproteins that terminate in D-mannose, L-fucose, or N-acetylglucosamine, as well as a variety of hormones. This receptor undergoes constitutive internalization and recycling between the plasma membrane and the endosomal compartment. CD206 is involved in antigen processing and presentation, cell migration, and intracellular signaling. Moreover, CD206 plays a key role in phagocytosis pathogens such as Candida albicans, Leishmania, and Mycobacterium tuberculosis.