CD205 Rat anti-Mouse, PE-Cy7, Clone: 205yekta, eBioscience™

Rat Monoclonal Antibody

Overview
Brand: Affymetrix eBioscience

Manufacturer Part Number: 25-2051-41

Code: NEW

Additional Details:
Additional Details: Weight: 0.23750kg



Disclaimers: For Research Use Only.

Product Code. 15538516

Quantity Price
1 £ 91.11 / 25 tests
Estimated Shipment date
from Supplier 03-05-2017
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Description and Specification

Specification

Applications Flow Cytometry
Conjugate PE-Cy7
Primary or Secondary Primary
Gene Alias DEC205, Ly75
Concentration 5μL (0.007μg)/test
Storage Requirements Store at 2-8°C. Do not freeze. Light-sensitive material. This tandem dye is sensitive to photo-induced oxidation. Protect this vial from light during storage
Isotype IgG2a
Monoclonal or Polyclonal Monoclonal
Antigen CD205
Species Reactivity Mouse
Host Species Rat
Clone 205yekta
Format Conjugated
Formulation aqueous buffer, 0.09% sodium azide, may contain carrier protein/stabilizer
Regulatory Status RUO
Quantity 25 tests

The 205yekta antibody reacts with mouse CD205, also known as DEC-205 (dendritic and epithelial cells, 205 kDa). CD205 is an integral membrane glycoprotein involved in antigen uptake, trafficking and presentation that improves the induction of antigen-specific T cell immunity. CD205 is highly expressed by CD8+ dendritic cells (DCs) and also expressed at different levels by bone marrow Gr1+ cells, Langerhans cells, (BMDC) bone marrow derived DCs and thymic epithelial cells.

CD205 has been shown to bind to PE-Cy5.5 antibody and streptavidin conjugates; therefore, this format should not be used on CD205+ dendritic cells.