CD205 Rat anti-Mouse, Alexa Fluor 488, Clone: 205yekta, eBioscience™

Rat Monoclonal Antibody

Overview
Brand: Affymetrix eBioscience

Manufacturer Part Number: 53-2051-82

UNSPSC: 12352200

Code: Z2

Additional Details:
Additional Details: Weight: 0.25000kg



Disclaimers: For Research Use Only.

Product Code. 15372010

Quantity Price
1 £ 158.36 / 100µg
Estimated Shipment date
from Supplier 03-04-2017
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Description and Specification

Specification

Clone 205yekta
Primary or Secondary Primary
Storage Requirements Store at 2-8°C. Do not freeze. Light-sensitive material.
Concentration 0.5mg/mL
Gene Alias DEC-205, Ly75
Formulation aqueous buffer, 0.09% sodium azide, may contain carrier protein/stabilizer
Quantity 100μg
Isotype IgG2a
Species Reactivity Mouse
Conjugate Alexa Fluor 488
Monoclonal or Polyclonal Monoclonal
Format Conjugated
Host Species Rat
Applications Flow Cytometry
Regulatory Status RUO
Antigen CD205

The 205yekta antibody reacts with mouse CD205, also known as DEC-205 (dendritic and epithelial cells, 205 kDa). CD205 is an integral membrane glycoprotein involved in antigen uptake, trafficking and presentation that improves the induction of antigen-specific T cell immunity. CD205 is highly expressed by CD8+ dendritic cells (DCs) and also expressed at different levels by bone marrow Gr1+ cells, Langerhans cells, (BMDC) bone marrow derived DCs and thymic epithelial cells.

CD205 has been shown to bind to PE-Cy5.5 antibody and streptavidin conjugates; therefore, this format should not be used on CD205+ dendritic cells.