missing translation for 'onlineSavingsMsg'
Learn More

CD201 (EPCR) Rat anti-Mouse, PE, Clone: eBio1560 (1560), eBioscience™

Rat Monoclonal Antibody

Brand:  Affymetrix eBioscience 12-2012-80

Code : Z2

Additional Details : Weight : 0.25000kg

 View more versions of this product

Product Code. 15218719

  • £72.77 / 25µg


Call for latest availability
+44 (0)1509 555 500
Add to basket

Disclaimers:

For Research Use Only.


Description

Description

The eBio1560 monoclonal antibody reacts with mouse Endothelial Protein C Receptor (EPCR, CD201), a 25kDa Type 1 transmembrane protein expressed on endothelial cells. EPCR exhibits sequence and structural homology with the MHC class I/CD1 family of proteins. EPCR is a ligand for Protein C and plays an important role in augmenting Protein C activation by the thrombin-thrombomodulin complex and in regulating blood coagulation and inflammation. Deletion of EPCR results in embryonic lethality, at least partically due to placental thrombosis.

Recently, it was demonstrated that EPCR expression identified cells in the bone marrow that are capable of hematopoietic reconstitution activity comparable to hematopoietic stem cells isolated with conventional methods. The eBio1560 monoclonal antibody can be used for the detection of these hematopoietic stem cells, however the eBiomRCR-16 monoclonal antibody should only be used for the detection of CD201 on endothelial cells.
Specifications

Specifications

CD201 (EPCR)
eBio1560 (1560)
PE
Conjugated
Rat
25μg
Store at 2-8°C. Do not freeze. Light-sensitive material.
Monoclonal
Flow Cytometry
0.2mg/mL
aqueous buffer, 0.09% sodium azide, may contain carrier protein/stabilizer
Endothelial Protein C Receptor
IgG2b
RUO
Primary
Murine
Videos