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CD201 (EPCR), Biotin, clone: eBio1560 (1560), eBioscience™

Rat Monoclonal Antibody

Brand:  Affymetrix eBioscience 13-2012-82

Code : Z2

Additional Details : Weight : 0.25000kg

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Product Code. 15249769

  • £174.50 / 100µg


EU Stock 1
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Disclaimers:

For Research Use Only.


Description

Description

Description: The eBio1560 monoclonal antibody reacts with mouse Endothelial Protein C Receptor (EPCR, CD201), a 25kDa Type 1 transmembrane protein expressed on endothelial cells. EPCR exhibits sequence and structural homology with the MHC class I/CD1 family of proteins. EPCR is a ligand for Protein C and plays an important role in augmenting Protein C activation by the thrombin-thrombomodulin complex and in regulating blood coagulation and inflammation. Deletion of EPCR results in embryonic lethality, at least partically due to placental thrombosis. Recently, it was demonstrated that EPCR expression identified cells in the bone marrow that are capable of hematopoietic reconstitution activity comparable to hematopoietic stem cells isolated with conventional methods. The eBio1560 monoclonal antibody can be used for the detection of these hematopoietic stem cells, however the eBiomRCR-16 monoclonal antibody should only be used for the detection of CD201 on endothelial cells.Applications Reported: This eBio1560 (1560) antibody has been reported for use in flow cytometric analysis, and immunohistochemical staining.Applications Tested: This eBio1560 (1560) antibody has been tested by flow cytometric analysis of bEnd.3 cells. This can be used at less than or equal to 1 μg per test. A test is defined as the amount (μg) of antibody that will stain a cell sample in a final volume of 100 μL. Cell number should be determined empirically but can range from 10^5 to 10^8 cells/test. It is recommended that the antibody be carefully titrated for optimal performance in the assay of interest, particμLarly when analyzing expression on endothelial cells where CD201 expression is very high.Filtration: 0.2μm post-manufacturing filtered.
Specifications

Specifications

CD201 (EPCR)
eBio1560 (1560)
Biotin
Conjugated
Rat
100μg
Store at 2-8°C. Do not freeze.
Monoclonal
Immunohistochemistry
0.5mg/mL
aqueous buffer, 0.09% sodium azide, may contain carrier protein/stabilizer
Endothelial Protein C Receptor
IgG2b
RUO
Primary
Murine
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