CD200 Mouse anti-Human, PE-Cy7, Clone: OX104, eBioscience™

Mouse Monoclonal Antibody

Overview
Brand: Affymetrix eBioscience

Manufacturer Part Number: 25-9200-41

Code: NEW

Additional Details:
Additional Details: Weight: 0.23750kg



Disclaimers: For Research Use Only.

Product Code. 15548656

Quantity Price
1 £ 97.22 / 25 tests
Estimated Shipment date
from Supplier 04-05-2017
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Description and Specification

Specification

Host Species Mouse
Regulatory Status RUO
Conjugate PE-Cy7
Isotype IgG1
Storage Requirements Store at 2-8°C. Do not freeze. Light-sensitive material. This tandem dye is sensitive to photo-induced oxidation. Protect this vial from light during storage
Clone OX104
Applications Flow Cytometry
Concentration 5μL (0.125μg)/test
Format Conjugated
Monoclonal or Polyclonal Monoclonal
Species Reactivity Human
Gene Alias OX-2
Primary or Secondary Primary
Formulation aqueous buffer, 0.09% sodium azide, may contain carrier protein/stabilizer
Antigen CD200
Quantity 25 tests

The monoclonal antibody OX104 recognizes human CD200 also known as OX2. CD200 is a member of the Ig superfamily with 2 Ig domains, a transmembrane and cytoplasmic domain. CD200 is expressed on resting and activated B cells, a subset of resting and activated T cells, keratinocytes, peripheral and central nerve cells, follicular dendritic cells and ovarian cells. The interaction with CD200R results in macrophage activation (IL-6 production), inhibition of mast cell degranulation along with reduced TNF alpha and IL-13 secretion and overall attenuation of the activation status of lymphocytes. A role has also been suggested in maternal tolerance as expression of CD200 is also present on the trophoblast.