CD200 Mouse anti-Human, FITC, Clone: OX104, eBioscience™

Mouse Monoclonal Antibody

Overview
Brand: Affymetrix eBioscience

Manufacturer Part Number: 11-9200-41

Code: NEW

Additional Details:
Additional Details: Weight: 0.23750kg



Disclaimers: For Research Use Only.

Product Code. 15576616

Quantity Price
1 £ 60.53 / 25 tests
Estimated Shipment date
from Supplier 04-05-2017
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Description and Specification

Specification

Gene Alias OX-2
Species Reactivity Human
Quantity 25 tests
Isotype IgG1
Monoclonal or Polyclonal Monoclonal
Formulation aqueous buffer, 0.09% sodium azide, may contain carrier protein/stabilizer
Storage Requirements Store at 2-8°C. Do not freeze. Light-sensitive material.
Clone OX104
Concentration 5μL (0.5μg)/test
Regulatory Status RUO
Applications Flow Cytometry
Conjugate FITC
Format Conjugated
Host Species Mouse
Antigen CD200
Primary or Secondary Primary

The monoclonal antibody OX104 recognizes human CD200 also known as OX2. CD200 is a member of the Ig superfamily with 2 Ig domains, a transmembrane and cytoplasmic domain. CD200 is expressed on resting and activated B cells, a subset of resting and activated T cells, keratinocytes, peripheral and central nerve cells, follicular dendritic cells and ovarian cells. The interaction with CD200R results in macrophage activation (IL-6 production), inhibition of mast cell degranulation along with reduced TNF alpha and IL-13 secretion and overall attenuation of the activation status of lymphocytes. A role has also been suggested in maternal tolerance as expression of CD200 is also present on the trophoblast.