CD200 Mouse anti-Human, Clone: OX104, eBioscience™

Mouse Monoclonal Antibody

Overview
Brand: Affymetrix eBioscience

Manufacturer Part Number: 14-9200-82

UNSPSC: 12352200

Code: Z2

Additional Details:
Additional Details: Weight: 0.01000kg



Disclaimers: For Research Use Only.

Product Code. 15248157

Quantity Price
1 £ 66.65 / 100µg
Estimated Shipment date
from Supplier 03-04-2017
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Description and Specification

Specification

Monoclonal or Polyclonal Monoclonal
Storage Requirements Store at 2-8°C.
Formulation aqueous buffer, 0.09% sodium azide, may contain carrier protein/stabilizer
Host Species Mouse
Concentration 0.5mg/mL
Format Purified
Gene Alias ox-2
Quantity 100μg
Clone OX104
Isotype IgG1
Conjugate Unlabeled
Applications Flow Cytometry
Applications Immunohistochemistry (Frozen)
Antigen CD200
Regulatory Status RUO
Species Reactivity Human
Primary or Secondary Primary

The monoclonal antibody OX104 recognizes human CD200 also known as OX2. CD200 is a member of the Ig superfamily with 2 Ig domains, a transmembrane and cytoplasmic domain. CD200 is expressed on resting and activated B cells, a subset of resting and activated T cells, keratinocytes, peripheral and central nerve cells, follicular dendritic cells and ovarian cells. The interaction with CD200R results in macrophage activation (IL-6 production), inhibition of mast cell degranulation along with reduced TNFα and IL-13 secretion and overall attenuation of the activation status of lymphocytes. A role has also been suggested in maternal tolerance as expression of CD200 is also present on the trophoblast.