CD20 Rat anti-Mouse, Clone: AISB12, Functional Grade, eBioscience™

Rat Monoclonal Antibody, Functional Grade

Overview
Brand: Affymetrix eBioscience

Manufacturer Part Number: 16-0201-82

UNSPSC: 12352200

Code: Z2

Additional Details:
Additional Details: Weight: 0.01000kg



Disclaimers: For Research Use Only.

Product Code. 15208407

Quantity Price
1 £ 78.88 / 100µg
EU Stock 2
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Description and Specification

Specification

Host Species Rat
Applications Flow Cytometry
Applications Functional Assay
Applications Western Blotting
Formulation aqueous buffer, no sodium azide
Isotype IgG2a
Format Purified
Antigen CD20
Regulatory Status RUO
Concentration 1mg/mL
Conjugate Unlabeled
Primary or Secondary Primary
Clone AISB12
Monoclonal or Polyclonal Monoclonal
Quantity 100μg
Species Reactivity Mouse
Storage Requirements Store at 2-8°C.

The AISB12 monoclonal antibody reacts with mouse CD20. CD20 is a B cell-specific 32kDa membrane protein involved in intracellular calcium regulation. CD20 expression begins after the induction of CD19 during development, and is coexpressed with IgM during the pre-B to immature B cell transition in bone marrow. Expression then increases during maturation with almost all mature cells expressing some level of CD20. The human CD20 antigen has proven to be an effective immunotherapeutic target in B cell lymphoma and several autoimmune diseases including rheumatoid arthritis and type I diabetes. CD20 consists of 4 transmembrane domains and a 44 amino acid extracellular loop domain where AISB12 binds.