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CD20, clone: AISB12, eBioscience™

Rat Monoclonal Antibody

Brand:  Affymetrix eBioscience 14-0201-82

Code : Z2

Additional Details : Weight : 0.01000kg

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Product Code. 15236847

  • £68.21 / 100µg


Estimated Shipment
29-06-2018
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Description

Description

Description: The AISB12 monoclonal antibody reacts with mouse CD20. CD20 is a B cell-specific 32kDa membrane protein involved in intracellular calcium regulation. CD20 expression begins after the induction of CD19 during development, and is coexpressed with IgM during the pre-B to immature B cell transition in bone marrow. Expression then increases during maturation with almost all mature cells expressing some level of CD20. The human CD20 antigen has proven to be an effective immunotherapeutic target in B cell lymphoma and several autoimmune diseases including rheumatoid arthritis and type I diabetes. CD20 consists of 4 transmembrane domains and a 44 amino acid extracellular loop domain where AISB12 binds.Applications Reported: This AISB12 antibody has been reported for use in flow cytometric analysis and western blotting.Applications Tested: This AISB12 antibody has been tested by immunoblot on A20 cell lysates and flow cytometry on mouse splenocytes.Purity: Greater than 90%, as determined by SDS-PAGE.Aggregation: Less than 10%, as determined by HPLC.Filtration: 0.2μm post-manufacturing filtered.
Specifications

Specifications

CD20
Monoclonal
0.5mg/mL
PBS with 0.09% sodium azide; pH 7.2
P19437
B1, Bp35, CD20, LEU-16, MGC3969, MS4A1
Rat
Affinity chromatography
RUO
Antibody
Monoclonal
Murine
Western Blot
AISB12
Unconjugated
Ms4a1
Purified
Ms4a1
IgG2a
100μg
Store at 2-8°C.
Primary
12482
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