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CD1d Mouse anti-Human, PerCP-eFluor 710, Clone: 51.1, eBioscience™

Mouse Monoclonal Antibody

Brand:  Affymetrix eBioscience 46-0016-41

Code : NEW

Additional Details : Weight : 0.23750kg

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Product Code. 15519056

  • £75.30 / 25 tests


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For Research Use Only.


Description

Description

The monoclonal antibody 51.1 reacts with human CD1d, a member of the CD1 family with similarity to the non-polymorphic MHC Class I-like molecules. CD1d is a highly conserved single transmembrane receptor of the Immunoglobulin Superfamily. CD1d can associate with beta-microglobulin another feature showing similarity to MHC class I molecules, but can also exist as a nonglycosylated protein not in association with beta microglobulin. This suggests different control mechanisms for presenting glycolipid containing molecules to CD1d reactive NKT cells. Expression of CD1d is found on B cells of the periphery, in resting monocytes and cortical thymocytes. On intestinal epithelial cells (IEC) expression is polarized. Expression can also be found at low levels intracellularly in hepatocytes. In HCV (hepatitis C virus) livers, CD1d is highly expressed compared to normal controls.

The 51.1 monoclonal antibody has been shown to have functional activity; blocking the interaction of CD1d transfected cells with NKT cells.
Specifications

Specifications

CD1d
51.1
PerCP-eFluor™ 710
Conjugated
Murine
25 Tests
Store at 2-8°C. Do not freeze. Light-sensitive material.
Monoclonal
Flow Cytometry
5μL (0.125μg)/test
aqueous buffer, 0.09% sodium azide, may contain carrier protein/stabilizer
R3, R3G1
IgG2b
RUO
Primary
Human
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