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CD1d Mouse anti-Human, PE, Clone: 51.1, eBioscience™

Mouse Monoclonal Antibody

Brand:  Affymetrix eBioscience 12-0016-41

Code : NEW

Additional Details : Weight : 0.23750kg

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Product Code. 15596666

  • £71.75 / 25 tests

Estimated Shipment
27-11-2020

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Description

Description

Cell number should be determined empirically but can range from 10^5 to 10^8 cells/test. Excitation: 488-561 nm; Emission: 578 nm; Laser: Blue Laser, Green Laser, Yellow-Green Laser. Filtration: 0.2 μm post-manufacturing filtered. CD1d is a 49 kDa heavy chain associated with Beta 2 microglobulin on cortical thymocytes. Beta 2 microglobulin independent expression of CD1d has also been demonstrated on human intestinal epithelial cells. CD1d is the sole group 2 member of the CD1 family of major histocompatibility (MHC) like glycoproteins. The CD1d gene encodes a divergent member of the CD1 family of transmembrane glycoproteins, which are structurally related to the major histocompatibility complex (MHC) proteins and form heterodimers with beta-2-microglobulin. The CD1 proteins mediate the presentation of primarily lipid and glycolipid antigens of self or microbial origin to T cells. The human genome contains five CD1 family genes organized in a cluster on chromosome 1. The CD1 family members are thought to differ in their cellular localization and specificity for particular lipid ligands. The protein encoded by the CD1d gene localizes to late endosomes and lysosomes via a tyrosine-based motif in the cytoplasmic tail. Diseases associated with CD1D include Mycobacterium Malmoense and Autoimmune Disease.
Specifications

Specifications

CD1d
Monoclonal
5 μL/Test
PBS with 0.1% gelatin, 0.2% BSA and 0.09% sodium azide; pH 7.2
P15813
AI747460, CD1.1, Cd1a, Cd1d, Ly-38, T-cell surface glycoprotein CD1d1, antigen-presenting glycoprotein CD1d1
Mouse
Affinity chromatography
RUO
Antibody
Monoclonal
Human
Flow Cytometry
51.1
PE
CD1D
Liquid
CD1D
IgG2b, kappa
25 Tests
4° C, store in dark, DO NOT FREEZE!
Primary
912
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