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CD1d, PE, clone: 51.1, eBioscience™

Mouse Monoclonal Antibody

Brand:  Affymetrix eBioscience 12-0016-41

Code : NEW

Additional Details : Weight : 0.23750kg

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Product Code. 15596666

  • £68.21 / 25 tests


Estimated Shipment date
from Supplier 23-07-2018
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Description

Description

Description: The monoclonal antibody 51.1 reacts with human CD1d, a member of the CD1 family with similarity to the non-polymorphic MHC Class I-like molecules. CD1d is a highly conserved single transmembrane receptor of the Immunoglobulin Superfamily. CD1d can associate with beta-microglobulin another feature showing similarity to MHC class I molecules, but can also exist as a nonglycosylated protein not in association with beta microglobulin. This suggests different control mechanisms for presenting glycolipid containing molecules to CD1d reactive NKT cells. Expression of CD1d is found on B cells of the periphery, in resting monocytes and cortical thymocytes. On intestinal epithelial cells (IEC) expression is polarized. Expression can also be found at low levels intracellularly in hepatocytes. In HCV (hepatitis C virus) livers, CD1d is highly expressed compared to normal controls.The 51.1 monoclonal antibody has been shown to have functional activity; blocking the interaction of CD1d transfected cells with NKT cells.Applications Reported: This 51.1 antibody has been reported for use in flow cytometric analysis.Applications Tested: This 51.1 antibody has been pre-titrated and tested by flow cytometric analysis of normal human peripheral blood cells. This can be used at 5 μL (0.125 μg) per test. A test is defined as the amount (μg) of antibody that will stain a cell sample in a final volume of 100 μL. Cell number should be determined empirically but can range from 10^5 to 10^8 cells/test.Excitation: 488-561 nm; Emission: 578 nm; Laser: Blue Laser, Green Laser, Yellow-Green Laser.Filtration: 0.2μm post-manufacturing filtered.
Specifications

Specifications

CD1d
Monoclonal
5μl/Test
PBS with 0.1% gelatin, 0.2% BSA and 0.09% sodium azide; pH 7.2
P15813
AI747460, CD1.1, Cd1a, Cd1d, Ly-38, T-cell surface glycoprotein CD1d1, antigen-presenting glycoprotein CD1d1
Murine
Affinity chromatography
RUO
Antibody
Monoclonal
Human
Flow Cytometry
51.1
PE
CD1D
Conjugated
CD1D
IgG2b, kappa
25 Tests
Store at 2-8°C. Do not freeze. Light-sensitive material.
Primary
912
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