CD1c Mouse anti-Human, PerCP-eFluor 710, Clone: L161, eBioscience™

Mouse Monoclonal Antibody

Overview
Brand: Affymetrix eBioscience

Manufacturer Part Number: 46-0015-41

Code: NEW

Additional Details:
Additional Details: Weight: 0.23750kg



Disclaimers: For Research Use Only.

Product Code. 15599046

Quantity Price
1 £ 113.26 / 25 tests
Estimated Shipment date
from Supplier 08-05-2017
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Description and Specification

Specification

Antigen CD1c
Format Conjugated
Storage Requirements Store at 2-8°C. Do not freeze. Light-sensitive material.
Applications Flow Cytometry
Primary or Secondary Primary
Isotype IgG1
Quantity 25 tests
Concentration 5μL (0.06μg)/test
Host Species Mouse
Regulatory Status RUO
Monoclonal or Polyclonal Monoclonal
Gene Alias BDCA-1
Species Reactivity Human
Formulation aqueous buffer, 0.09% sodium azide, may contain carrier protein/stabilizer
Conjugate PerCP-eFluor 710
Clone L161

This L161 monoclonal antibody detects CD1c (also known as BDCA-1), a glycoprotein that is noncovalently linked to beta-2 microglobulin on thymocytes and antigen presenting cells such as dendritic and Langerhans cells. This molecule is also expressed on some circulating and marginal zone B cells, as well as in lymph nodes and germinal centers. CD1c is involved in the presentation of lipid antigens such as microbial fatty acids to effector T cells during the adaptive immune response. Finally, alternative splicing gives rise to three different isoforms of CD1c (soluble, membrane, and cytoplasmic/soluble isoforms).