CD1c Mouse anti-Human, PE-Cy7, Clone: L161, eBioscience™

Mouse Monoclonal Antibody

Overview
Brand: Affymetrix eBioscience

Manufacturer Part Number: 25-0015-42

Code: NEW

Additional Details:
Additional Details: Weight: 0.23750kg



Disclaimers: For Research Use Only.

Product Code. 15528326

Quantity Price
1 £ 201.16 / 100 tests
EU Stock 2
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Description and Specification

Specification

Species Reactivity Human
Clone L161
Antigen CD1c
Formulation aqueous buffer, 0.09% sodium azide, may contain carrier protein/stabilizer
Host Species Mouse
Quantity 100 tests
Format Conjugated
Concentration 5μL (0.125μg)/test
Gene Alias BDCA-1
Primary or Secondary Primary
Regulatory Status RUO
Conjugate PE-Cy7
Monoclonal or Polyclonal Monoclonal
Isotype IgG1
Storage Requirements Store at 2-8°C. Do not freeze. Light-sensitive material. This tandem dye is sensitive to photo-induced oxidation. Protect this vial from light during storage
Applications Flow Cytometry

This L161 monoclonal antibody detects CD1c (also known as BDCA-1), a glycoprotein that is noncovalently linked to beta-2 microglobulin on thymocytes and antigen presenting cells such as dendritic and Langerhans cells. This molecule is also expressed on some circulating and marginal zone B cells, as well as in lymph nodes and germinal centers. CD1c is involved in the presentation of lipid antigens such as microbial fatty acids to effector T cells during the adaptive immune response. Finally, alternative splicing gives rise to three different isoforms of CD1c (soluble, membrane, and cytoplasmic/soluble isoforms).