CD1c Mouse anti-Human, PE-Cy7, Clone: L161, eBioscience™

Mouse Monoclonal Antibody

Overview
Brand: Affymetrix eBioscience

Manufacturer Part Number: 25-0015-41

Code: NEW

Additional Details:
Additional Details: Weight: 0.23750kg



Disclaimers: For Research Use Only.

Product Code. 15518326

Quantity Price
1 £ 78.88 / 25 tests
Estimated Shipment date
from Supplier 02-05-2017
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Description and Specification

Specification

Quantity 25 tests
Host Species Mouse
Primary or Secondary Primary
Species Reactivity Human
Storage Requirements Store at 2-8°C. Do not freeze. Light-sensitive material. This tandem dye is sensitive to photo-induced oxidation. Protect this vial from light during storage
Antigen CD1c
Regulatory Status RUO
Applications Flow Cytometry
Isotype IgG1
Format Conjugated
Monoclonal or Polyclonal Monoclonal
Conjugate PE-Cy7
Gene Alias BDCA-1
Clone L161
Concentration 5μL (0.125μg)/test
Formulation aqueous buffer, 0.09% sodium azide, may contain carrier protein/stabilizer

This L161 monoclonal antibody detects CD1c (also known as BDCA-1), a glycoprotein that is noncovalently linked to beta-2 microglobulin on thymocytes and antigen presenting cells such as dendritic and Langerhans cells. This molecule is also expressed on some circulating and marginal zone B cells, as well as in lymph nodes and germinal centers. CD1c is involved in the presentation of lipid antigens such as microbial fatty acids to effector T cells during the adaptive immune response. Finally, alternative splicing gives rise to three different isoforms of CD1c (soluble, membrane, and cytoplasmic/soluble isoforms).