CD199 (CCR9) Mouse anti-Mouse, eFluor 450, Clone: eBioCW-1.2 (CW-1.2), eBioscience™

Mouse Monoclonal Antibody

Overview
Brand: Affymetrix eBioscience

Manufacturer Part Number: 48-1991-82

UNSPSC: 12352200

Code: Z2

Additional Details:
Additional Details: Weight: 0.25000kg



Disclaimers: For Research Use Only.

Product Code. 15331760

Quantity Price
1 £ 176.7 / 100µg
Estimated Shipment date
from Supplier 05-05-2017
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Description and Specification

Specification

Host Species Murine
Formulation aqueous buffer, 0.09% sodium azide, may contain carrier protein/stabilizer
Monoclonal or Polyclonal Monoclonal
Antigen CD199 (CCR9)
Format Conjugated
Applications Flow Cytometry
Conjugate eFluor 450
Quantity 100μg
Primary or Secondary Primary
Species Reactivity Mouse
Isotype IgG2a
Regulatory Status RUO
Concentration 0.2mg/mL
Storage Requirements Store at 2-8°C. Do not freeze. Light-sensitive material.
Clone eBioCW-1.2 (CW-1.2)

The eBioCW-1.2 monoclonal antibody reacts with mouse CCR9 (CD199), which is the receptor for thymus-expressed chemokine (TECK). CCR9 is a member of the G protein coupled receptor (GPCR) supergene family, and is involved in trafficking of T cell progenitors within the thymus. CCR9 expression during thymocyte development commences at the double-negative (DN) 3 stage (CD4-CD8-CD25+CD44-), peaks in the double-positive (DP) stage (CD4+CD8+CD25-CD44-), and is down-regulated in commited CD4+ or CD8+ single-positive (SP) thymoyctes. CCR9-deficient mice show a mild impairment in thymoycte development. In the periphery, CCR9 is thought to be expressed on naïve CD8+ T cells, but not on naïve CD4+ T cells.