CD196 (CCR6) Mouse anti-Human, APC, Clone: R6H1, eBioscience™

Mouse Monoclonal Antibody

Overview
Brand: Affymetrix eBioscience

Manufacturer Part Number: 17-1969-42

Code: NEW

Additional Details:
Additional Details: Weight: 0.23750kg



Disclaimers: For Research Use Only.

Product Code. 15578046

Quantity Price
1 £ 176.7 / 100 tests
Estimated Shipment date
from Supplier 03-04-2017
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Description and Specification

Specification

Species Reactivity Human
Formulation aqueous buffer, 0.09% sodium azide, may contain carrier protein/stabilizer
Quantity 100 tests
Storage Requirements Store at 2-8°C. Do not freeze. Light-sensitive material.
Host Species Mouse
Applications Flow Cytometry
Clone R6H1
Isotype IgG1
Regulatory Status RUO
Monoclonal or Polyclonal Monoclonal
Primary or Secondary Primary
Conjugate APC
Format Conjugated
Antigen CD196 (CCR6)
Concentration 5μL (0.25μg)/test

This R6H1 monoclonal antibody reacts with CD196 (also known as CCR6), a seven transmembrane G protein-coupled receptor expressed on T, B, dendritic, natural killer, and Langerhans cells. This CC chemokine receptor uniquely binds MIP-3a/CCL20, a chemoattractant for dendritic cells, effector/memory T cells, and B cells. CD196 is also involved in host defense and inflammation at epithelial sites. Furthermore, this receptor has been implicated in Th17 differentiation and CD4+FoxP3+ regulatory T cell development.