CD195 (CCR5), APC, clone: NP-6G4, eBioscience™
Mouse Monoclonal Antibody
Brand: Affymetrix eBioscience 17-1956-41
Code : NEW
Additional Details : Weight : 0.23750kg
DescriptionDescription: The NP-6G4 monoclonal antibody reacts with human CD195 (CCR5), an approximately 45kDa member of the G protein-coupled receptor (GPCR) superfamily that binds chemokines including MIP-1a, MIP-1b and RANTES. Human CCR5 is expressed on resting T cells with a memory/effector phenotype, monocytes, macrophages and immature dendritic cells. CCR5 functions as a receptor to direct the chemotaxis of lymphocytes, and is the primary co-receptor for macrophage-tropic Human Immunodeficiency Virus Type 1 (HIV-1), which binds CCR5 through gp120.Applications Reported: This NP-6G4 antibody has been reported for use in flow cytometric analysis.Applications Tested: This NP-6G4 antibody has been pre-titrated and tested on normal human peripheral blood cells. For optimal performance, it is recommended that staining with NP-6G4 be done at 37°C for 30 to 60 minutes in Flow Cytometry Staining Buffer. This antibody can be used at 5 μL (0.25 μg) per test. A test is defined as the amount (μg) of antibody that will stain a cell sample in a final volume of 100 μL. Cell number should be determined empirically but can range from 10^5 to 10^8 cells/test.Excitation: 633-647 nm; Emission: 660 nm; Laser: Red Laser.Filtration: 0.2μm post-manufacturing filtered.
|PBS with 0.1% gelatin, 0.2% BSA and 0.09% sodium azide; pH 7.2|
|C-C CKR-5, CC-CKR-5, HIV-1 fusion coreceptor, CHEMR13, CD195 antigen, CMKBR5|
|Store at 2-8°C. Do not freeze. Light-sensitive material.|
For Research Use Only.