CD195 (CCR5) Armenian Hamster anti-Mouse, PE, Clone: HM-CCR5 (7A4), eBioscience™

Armenian Hamster Monoclonal Antibody

Overview
Brand: Affymetrix eBioscience

Manufacturer Part Number: 12-1951-81

UNSPSC: 12352200

Code: Z2

Additional Details:
Additional Details: Weight: 0.25000kg



Disclaimers: For Research Use Only.

Product Code. 15228709

Quantity Price
1 £ 66.65 / 50µg
EU Stock 2
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Description and Specification

Specification

Format Conjugated
Formulation aqueous buffer, 0.09% sodium azide, may contain carrier protein/stabilizer
Monoclonal or Polyclonal Monoclonal
Storage Requirements Store at 2-8°C. Do not freeze. Light-sensitive material.
Clone HM-CCR5 (7A4)
Regulatory Status RUO
Antigen CD195 (CCR5)
Concentration 0.2mg/mL
Quantity 50μg
Host Species Armenian Hamster
Applications Flow Cytometry
Isotype IgG
Primary or Secondary Primary
Conjugate PE
Gene Alias MIP-1 alpha Receptor C-C chemokine receptor type 5, Cmkbr5
Species Reactivity Mouse

CCR5 is the major co-receptor for macrophage-tropic isolates of HIV-1. CCR5, also known as CD195, is a seven transmembrane chemokine receptor capable of binding RANTES, MIP-1 alpha and MIP-1 beta. Knockout mice show a decreased recruitment of macrophages and increased susceptibility to infection. Protein and mRNA has been found in macrophages from thioglycolate-treated and activated T cells.

The HM-CCR5(7A4) monoclonal antibody binds the N terminal extracellular domain of mouse CCR5 with no crossreactivity to human CCR5.