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CD193 (CCR3) Mouse anti-Human, APC, Clone: 5E8-G9-B4, eBioscience™

Mouse Monoclonal Antibody

Brand:  Affymetrix eBioscience 17-1939-42

Code : NEW

Additional Details : Weight : 0.23750kg

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Product Code. 15518046

  • £182.82 / 100 tests


EU Stock 2
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Disclaimers:

For Research Use Only.


Description

Description

The eBio5E8-G9-B4 monoclonal antibody reacts with human CD193 (CCR3, CKR3). CD193 is a member of the seven transmembrane G-protein coupled receptor (GPCR) family, and is a high affinity chemokine receptor for the chemokines eotaxin-1 (CCL11), eotaxin-2 (CCL24), eotaxin-3 (CCL26) and MCP-4 (CCL13), but has also been reported to bind RANTES, MCP-3 and MCP-4. CD193 is highly expressed on the surface of eosinophils, and is the key eosinophil chemokine receptor responsible for the regulation of eosinophil migration and function. In addition to eosinophils, CD193 is also expressed on CD4+ TH2 cells, basophils, mast cells, mononuclear phagocytes, platelets, CD34+ hematopoietic progenitors and airway epithelial cells. CD193 likely plays an important role in the migration of eosinophils in allergic airway inflammation and asthma. CD193 can also serve as a receptor for HIV-1 cell entry.
Specifications

Specifications

CD193 (CCR3)
eBio5E8-G9-B4 (5E8-G9-B4)
APC
Conjugated
Murine
100 Tests
Store at 2-8°C. Do not freeze. Light-sensitive material.
Monoclonal
Flow Cytometry
5μL (0.25μg)/test
aqueous buffer, 0.09% sodium azide, may contain carrier protein/stabilizer
CKR3
IgG2b
RUO
Primary
Human