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CD19, clone: LC1, eBioscience™

Mouse Monoclonal Antibody

Brand:  Affymetrix eBioscience 14-0190-80

Code : Z2

Additional Details : Weight : 0.01000kg

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Product Code. 15206837

  • £30.83 / 25µg


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For Research Use Only.


Description

Description

Description: The LC1 monoclonal antibody reacts with human CD19, a 95kDa transmembrane glycoprotein. CD19 is expressed by B cells during all stages of development excluding the terminally differentiated plasma cells. Follicular dendritic cells also express CD19. Together CD21, CD81, Leu13, MHC class II, and CD19 form a multi-molecular complex that associates with BCR. Signaling through CD19 induces tyrosine phosphorylation, calcium flux and proliferation of B cells. The antibody recognizes a sequence near the carboxy terminus.Applications Reported: This LC1 antibody has been reported for use in western blotting and immunohistochemical staining of formalin-fixed paraffin embedded tissue sections.Applications Tested: This LC1 antibody has been tested by western blot and can be used at less than or equal to 5 μg/mL. This antibody has also been tested by immunohistochemistry on FFPE human tonsil using high pH antigen retrieval at less than or equal to 10 μg/mL. It is recommended that the antibody be carefully titrated for optimal performance in the assay of interest.Purity: Greater than 90%, as determined by SDS-PAGE.Aggregation: Less than 10%, as determined by HPLC.Filtration: 0.2μm post-manufacturing filtered.
Specifications

Specifications

CD19
LC1
Unconjugated
Purified
Murine
25μg
Store at 2-8°C.
Monoclonal
Western Blot
0.5mg/mL
aqueous buffer, 0.09% sodium azide, may contain carrier protein/stabilizer
Leu-12
IgG1
RUO
Primary
Human
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