CD183 (CXCR3) Mouse anti-Human, PE-eFluor 610, Clone: CEW33D, eBioscience™

Mouse Monoclonal Antibody

Overview
Brand: Affymetrix eBioscience

Manufacturer Part Number: 61-1839-41

Code: NEW

Additional Details:
Additional Details: Weight: 0.23750kg



Disclaimers: For Research Use Only.

Product Code. 15590467

Quantity Price
1 £ 91.11 / 25 tests
Estimated Shipment date
from Supplier 03-04-2017
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Description and Specification

Specification

Concentration 5μL (0.5μg)/test
Host Species Mouse
Isotype IgG1
Storage Requirements Store at 2-8°C. Do not freeze. Light-sensitive material. This tandem dye is sensitive to photo-induced oxidation. Protect this vial from light during storage
Clone CEW33D
Gene Alias C-X-C chemokine receptor type 3, CXC-R3, GPR9
Regulatory Status RUO
Monoclonal or Polyclonal Monoclonal
Conjugate PE-eFluor 610
Quantity 25 tests
Primary or Secondary Primary
Applications Flow Cytometry
Format Conjugated
Species Reactivity Human
Antigen CD183 (CXCR3)
Formulation aqueous buffer, 0.09% sodium azide, may contain carrier protein/stabilizer

The CEW33D monoclonal antibody reacts with human CD183. CD183, also known as CXCR3, is a G protein-coupled chemokine receptor that interacts with ligands CXCL9 (MIG), CXCL10 (IP-10), and CXCL11 (I-TAC). Strongly associated with type 1 immunity, CD183 is induced in naïve T cells upon activation and remains upregulated in T helper type (Th)1 cells, CD8 effector cells, NK cells and NKT cells. CD183-ligand interactions mediate infiltration of inflamed tissues in normal type 1 immune responses as well as in many inflammatory and autoimmune diseases. CD183 is also expressed on some B cells and plasmacytoid DC.