CD183 (CXCR3) Mouse anti-Human, eFluor 660, Clone: CEW33D, eBioscience™

Mouse Monoclonal Antibody

Overview
Brand: Affymetrix eBioscience

Manufacturer Part Number: 50-1839-42

Code: NEW

Additional Details:
Additional Details: Weight: 0.23750kg



Disclaimers: For Research Use Only.

Product Code. 15549916

Quantity Price
1 £ 182.82 / 100 tests
Estimated Shipment date
from Supplier 02-05-2017
Add to basket


Description and Specification

Specification

Antigen CD183 (CXCR3)
Gene Alias C-X-C chemokine receptor type 3, CXC-R3, GPR9
Storage Requirements Store at 2-8°C. Do not freeze. Light-sensitive material.
Formulation aqueous buffer, 0.09% sodium azide, may contain carrier protein/stabilizer
Host Species Mouse
Species Reactivity Human
Regulatory Status RUO
Quantity 100 tests
Format Conjugated
Isotype IgG1
Concentration 5μL (0.5μg)/test
Conjugate eFluor 660
Clone CEW33D
Primary or Secondary Primary
Monoclonal or Polyclonal Monoclonal
Applications Flow Cytometry

The CEW33D monoclonal antibody reacts with human CD183. CD183, also known as CXCR3, is a G protein-coupled chemokine receptor that interacts with ligands CXCL9 (MIG), CXCL10 (IP-10), and CXCL11 (I-TAC). Strongly associated with type 1 immunity, CD183 is induced in naïve T cells upon activation and remains upregulated in T helper type (Th)1 cells, CD8 effector cells, NK cells and NKT cells. CD183-ligand interactions mediate infiltration of inflamed tissues in normal type 1 immune responses as well as in many inflammatory and autoimmune diseases. CD183 is also expressed on some B cells and plasmacytoid DC.