CD18 Rat anti-Mouse, FITC, Clone: M18/2, eBioscience™

Rat Monoclonal Antibody

Overview
Brand: Affymetrix eBioscience

Manufacturer Part Number: 11-0181-81

UNSPSC: 12352200

Code: Z2

Additional Details:
Additional Details: Weight: 0.25000kg



Disclaimers: For Research Use Only.

Product Code. 15218039

Quantity Price
1 £ 48.31 / 50µg
Estimated Shipment date
from Supplier 04-05-2017
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Description and Specification

Specification

Gene Alias Integrin beta 2, ITGB2
Concentration 0.5mg/mL
Species Reactivity Mouse
Clone M18/2
Monoclonal or Polyclonal Monoclonal
Formulation aqueous buffer, 0.09% sodium azide, may contain carrier protein/stabilizer
Host Species Rat
Conjugate FITC
Quantity 50μg
Antigen CD18
Format Conjugated
Applications Flow Cytometry
Regulatory Status RUO
Primary or Secondary Primary
Isotype IgG2a
Storage Requirements Store at 2-8°C. Do not freeze. Light-sensitive material.

The M18/2 monoclonal antibody reacts with mouse CD18, the 90-95kDa integrin beta 2 glycoprotein. CD18 is the common β subunit that non-covalently associates with CD11a (alpha L), CD11b (alpha M) and CD11c (alpha X) to form LFA-1, Mac-1 and gp150/95. Heterodimers of CD18 and the a subunits are expressed broadly by all leukocytes with NK and T cells showing higher density of surface expression. Through the interactions of LFA-1, Mac-1 and gp150/95 with their counter-receptors, CD18 is involved in cellular adhesion and the immune response.