CD18 Rat anti-Mouse, Clone: M18/2, Functional Grade, eBioscience™

Rat Monoclonal Antibody, Functional Grade

Overview
Brand: Affymetrix eBioscience

Manufacturer Part Number: 16-0181-85

UNSPSC: 12352200

Code: Z2

Additional Details:
Additional Details: Weight: 0.01000kg



Disclaimers: For Research Use Only.

Product Code. 15248397

Quantity Price
1 £ 170.59 / 500µg
Estimated Shipment date
from Supplier 04-05-2017
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Description and Specification

Specification

Isotype IgG2a
Species Reactivity Mouse
Regulatory Status RUO
Monoclonal or Polyclonal Monoclonal
Applications Flow Cytometry
Applications Functional Assay
Quantity 500μg
Primary or Secondary Primary
Gene Alias Integrin beta 2, ITGB2
Formulation aqueous buffer, no sodium azide
Concentration 1mg/mL
Clone M18/2
Conjugate Unlabeled
Antigen CD18
Storage Requirements Store at 2-8°C.
Format Purified
Host Species Rat

The M18/2 monoclonal antibody reacts with mouse CD18, the 90-95kDa integrin beta 2 glycoprotein. CD18 is the common β subunit that non-covalently associates with CD11a (alpha L), CD11b (alpha M) and CD11c (alpha X) to form LFA-1, Mac-1 and gp150/95. Heterodimers of CD18 and the a subunits are expressed broadly by all leukocytes with NK and T cells showing higher density of surface expression. Through the interactions of LFA-1, Mac-1 and gp150/95 with their counter-receptors, CD18 is involved in cellular adhesion and the immune response.