CD18 Rat anti-Mouse, Clone: M18/2, eBioscience™

Rat Monoclonal Antibody

Overview
Brand: Affymetrix eBioscience

Manufacturer Part Number: 14-0181-81

UNSPSC: 12352200

Code: Z2

Additional Details:
Additional Details: Weight: 0.01000kg



Disclaimers: For Research Use Only.

Product Code. 15276827

Quantity Price
1 £ 29.97 / 50µg
Estimated Shipment date
from Supplier 05-05-2017
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Description and Specification

Specification

Format Purified
Monoclonal or Polyclonal Monoclonal
Primary or Secondary Primary
Applications Flow Cytometry
Applications Functional Assay
Applications Immunohistochemistry
Applications Immunoprecipitation
Applications Western Blotting
Formulation aqueous buffer, 0.09% sodium azide, may contain carrier protein/stabilizer
Species Reactivity Mouse
Antigen CD18
Isotype IgG2a
Regulatory Status RUO
Clone M18/2
Gene Alias Integrin beta 2, ITGB2
Storage Requirements Store at 2-8°C.
Host Species Rat
Concentration 0.5mg/mL
Quantity 50μg
Conjugate Unlabeled

The M18/2 monoclonal antibody reacts with mouse CD18, the 90-95kDa integrin beta 2 glycoprotein. CD18 is the common β subunit that non-covalently associates with CD11a (alpha L), CD11b (alpha M) and CD11c (alpha X) to form LFA-1, Mac-1 and gp150/95. Heterodimers of CD18 and the a subunits are expressed broadly by all leukocytes with NK and T cells showing higher density of surface expression. Through the interactions of LFA-1, Mac-1 and gp150/95 with their counter-receptors, CD18 is involved in cellular adhesion and the immune response.