CD18 Rat anti-Mouse, Clone: M18/2, eBioscience™

Rat Monoclonal Antibody

Overview
Brand: Affymetrix eBioscience

Manufacturer Part Number: 14-0181-85

500UG:ANTI-MOUSE CD18 PURIFIED 500 UG

UNSPSC: 12352200

Code: Z2

Additional Details:
Additional Details: Weight: 0.01000kg



Disclaimers: For Research Use Only.

Product Code. 15296827

Quantity Price
1 £ 140.02 / 500µg
Estimated Shipment date
from Supplier 30-03-2017
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Description and Specification

Specification

Antigen CD18
Format Purified
Formulation aqueous buffer, 0.09% sodium azide, may contain carrier protein/stabilizer
Gene Alias Integrin beta 2, ITGB2
Host Species Rat
Applications Flow Cytometry
Applications Functional Assay
Applications Immunohistochemistry
Applications Immunoprecipitation
Applications Western Blotting
Isotype IgG2a
Quantity 500μg
Regulatory Status RUO
Species Reactivity Mouse
Storage Requirements Store at 2-8°C.
Primary or Secondary Primary
Monoclonal or Polyclonal Monoclonal
Clone M18/2
Concentration 0.5mg/mL
Conjugate Unlabeled

The M18/2 monoclonal antibody reacts with mouse CD18, the 90-95kDa integrin beta 2 glycoprotein. CD18 is the common β subunit that non-covalently associates with CD11a (alpha L), CD11b (alpha M) and CD11c (alpha X) to form LFA-1, Mac-1 and gp150/95. Heterodimers of CD18 and the a subunits are expressed broadly by all leukocytes with NK and T cells showing higher density of surface expression. Through the interactions of LFA-1, Mac-1 and gp150/95 with their counter-receptors, CD18 is involved in cellular adhesion and the immune response.