CD178 (CD95 Ligand) Mouse anti-Human, Clone: NOK-1, Functional Grade, eBioscience™

Mouse Monoclonal Antibody, Functional Grade

Overview
Brand: Affymetrix eBioscience

Manufacturer Part Number: 16-9919-81

UNSPSC: 12352200

Code: Z2

Additional Details:
Additional Details: Weight: 0.01000kg



Disclaimers: For Research Use Only.

Product Code. 15248837

Quantity Price
1 £ 66.65 / 50µg
Estimated Shipment date
from Supplier 05-05-2017
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Description and Specification

Specification

Host Species Mouse
Antigen CD178 (CD95 Ligand)
Regulatory Status RUO
Quantity 50μg
Applications Flow Cytometry
Applications Functional Assay
Isotype IgG1
Gene Alias CD95L, Fas ligand, FasL
Monoclonal or Polyclonal Monoclonal
Primary or Secondary Primary
Format Purified
Clone NOK-1
Storage Requirements Store at 2-8°C.
Concentration 1mg/mL
Formulation aqueous buffer, no sodium azide
Conjugate Unlabeled
Species Reactivity Human

The NOK-1 monoclonal antibody reacts with human Fas (CD95) Ligand, a 40kDa type II transmembrane glycoprotein. FasL is a member of the TNF family and is expressed by neutrophils, monocytes, and activated T cells and NK cells. The interaction of FasL with its receptor (CD95, Fas) induces Fas-mediated killing of lymphocytes. Human FasL is cleaved from the surface by matrix metalloproteinases (MMPs), resulting in a 26kDa soluble form. Therefore for optimal detection of surface FasL on activated peripheral blood cells, incubation of cells with an MMP inhibitor is recommended.