CD177 Mouse anti-Human, eFluor 660, Clone: MEM-166 (MEM166), eBioscience™

Mouse Monoclonal Antibody

Overview
Brand: Affymetrix eBioscience

Manufacturer Part Number: 50-1779-42

Code: NEW

Additional Details:
Additional Details: Weight: 0.23750kg



Disclaimers: For Research Use Only.

Product Code. 15529916

Quantity Price
1 £ 121.67 / 100 tests
Estimated Shipment date
from Supplier 03-04-2017
Add to basket


Description and Specification

Specification

Format Conjugated
Antigen CD177
Regulatory Status RUO
Conjugate eFluor 660
Applications Flow Cytometry
Isotype IgG1
Primary or Secondary Primary
Gene Alias neutrophil-specific antigen, NB1, NB-1
Concentration 5μL (0.015μg)/test
Clone MEM-166 (MEM166)
Storage Requirements Store at 2-8°C. Do not freeze. Light-sensitive material.
Formulation aqueous buffer, 0.09% sodium azide, may contain carrier protein/stabilizer
Host Species Mouse
Species Reactivity Human
Monoclonal or Polyclonal Monoclonal
Quantity 100 tests

The MEM-166 monoclonal antibody reacts with human CD177, a 58-64kDa GPI-anchored glycoprotein. The human CD177 locus codes for at least two alleles, NB1 and PRV-1, which differ by only 4 amino acids. CD177 is expressed on granulocytes, early erythroblasts, megakaryocytes, promyelocytes and myelocytes. CD177 mRNA levels are elevated in several different myeloproliferative disorders including polycythemia vera, and antibodies to CD177 are involved in neonatal alloimmune neutropenia, autoimmune drug induced neutropenia, and graft failure following marrow transplantation.