CD170 (Siglec F) Rat anti-Mouse, PerCP-eFluor 710, Clone: 1RNM44N, eBioscience™

Rat Monoclonal Antibody

Brand:  Affymetrix eBioscience 46-1702-80

Product Code. 15529206

Disclaimers:

For Research Use Only.

Description

This 1RNM44N monoclonal antibody recognizes mouse CD170, also known as Siglec F. Siglec F is a cell surface lectin belonging to the Ig superfamily that binds glycoconjugates containing sialic acids that are commonly found on various cell types. The cytoplasmic domain of Siglec F contains an immunoreceptor tyrosine-based inhibitory motif (ITIM) that initiates intracellular signaling upon ligand binding. Siglec F is expressed mostly on eosinophils and alveolar macrophages and lower levels of this receptor have also been reported on immature myelomonocytic cells. Mouse Siglec F is a functional ortholog of human Siglec 8, however, unlike human Siglec 8, mouse Siglec F is not expressed on mast cells.

This 1RNM44N antibody will recognize a formaldehyde-fixed epitope.

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Specifications

• Antigen: CD170 (Siglec F)
• Clone: 1RNM44N
• Conjugate: PerCP-eFluor 710
• Format: Conjugated
• Isotype: IgG2a
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Target Species: Murine

• Applications: Flow Cytometry
• Concentration: 0.2mg/mL
• Formulation: aqueous buffer, 0.09% sodium azide, may contain carrier protein/stabilizer
• Host Species: Rat
• Quantity: 25μg
• Storage Requirements: Store at 2-8°C. Do not freeze. Light-sensitive material. This tandem dye is sensitive to photo-induced oxidation. Protect this vial from light during storage
• Monoclonal or Polyclonal: Monoclonal