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CD170 (Siglec F) Monoclonal Antibody (1RNM44N), eFluor™ 660, eBioscience™, Invitrogen™

Rat Monoclonal Antibody

£111.00 - £249.00

Specifications

Antigen CD170 (Siglec F)
Clone 1RNM44N
Concentration 0.2 mg/mL
Applications Flow Cytometry
Classification Monoclonal
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Products 2
Product Code Brand Quantity Price Quantity & Availability  
Product Code Brand Quantity Price Quantity & Availability  
15599906
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Affymetrix eBioscience
50-1702-80
25 μg
£111.00
25µg
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15509916
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Affymetrix eBioscience
50-1702-82
100 μg
£249.00
100µg
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Estimated Shipment: 09-04-2024
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Description

Description

Description: This 1RNM44N monoclonal antibody recognizes mouse CD170, also known as Siglec F. Siglec F is a cell surface lectin belonging to the Ig superfamily that binds glycoconjugates containing sialic acids that are commonly found on various cell types. The cytoplasmic domain of Siglec F contains an immunoreceptor tyrosine-based inhibitory motif (ITIM) that initiates intracellular signaling upon ligand binding. Siglec F is expressed mostly on eosinophils and alveolar macrophages and lower levels of this receptor have also been reported on immature myelomonocytic cells. Mouse Siglec F is a functional ortholog of human Siglec 8, however, unlike human Siglec 8, mouse Siglec F is not expressed on mast cells. This 1RNM44N antibody will recognize a formaldehyde-fixed epitope. Applications Reported: This 1RNM44N antibody has been reported for use in flow cytometric analysis. Applications Tested: This 1RNM44N antibody has been tested by flow cytometric analysis of mouse thioglycolate-elicited peritoneal exudate cells. This can be used at less than or equal to 0.125 μg per test. A test is defined as the amount (μg) of antibody that will stain a cell sample in a final volume of 100 μL. Cell number should be determined empirically but can range from 10^5 to 10^8 cells/test. It is recommended that the antibody be carefully titrated for optimal performance in the assay of interest.

CD170 (Siglec F) Monoclonal antibody specifically detects CD170 (Siglec F) in Mouse samples. It is validated for Flow Cytometry.
Specifications

Specifications

CD170 (Siglec F)
0.2 mg/mL
Monoclonal
Liquid
RUO
PBS with 0.09% sodium azide; pH 7.2
CD170; CD33 antigen-like 2; CD33L2; mSiglec-F; OB-binding protein 2; OBBP2; OB-BP2; Obesity-binding protein 2; sialic acid binding Ig like lectin 5; sialic acid binding Ig-like lectin 5; sialic acid binding Ig-like lectin F; sialic acid-binding Ig-like lectin 5; Sialic acid-binding Ig-like lectin F; sialic acid-binding immunoglobulin-like lectin 5; sialic acid-binding lectin Siglec-F; Siglec; SIGLEC5; siglec-5; Siglecf; Siglec-F
Siglecf
Primary
4° C, store in dark, DO NOT FREEZE!
Siglecf
1RNM44N
Flow Cytometry
eFluor 660
Rat
Mouse
Q920G3
233186
IgG2a κ
Affinity chromatography
Antibody
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