CD170 (Siglec F) Rat anti-Mouse, Clone: 1RNM44N, eBioscience™

Rat Monoclonal Antibody

Overview
Brand: Affymetrix eBioscience

Manufacturer Part Number: 14-1702-82

Code: NEW

Additional Details:
Additional Details: Weight: 0.09500kg



Disclaimers: For Research Use Only.

Product Code. 15537436

Quantity Price
1 £ 161.27 / 100µg
EU Stock 2
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Description and Specification

Specification

Storage Requirements Store at 2-8°C.
Quantity 100μg
Antigen CD170 (Siglec F)
Regulatory Status RUO
Applications Flow Cytometry
Applications Immunohistochemistry (Frozen)
Concentration 0.5mg/mL
Species Reactivity Mouse
Formulation aqueous buffer, 0.09% sodium azide, may contain carrier protein/stabilizer
Conjugate Unlabeled
Primary or Secondary Primary
Format Purified
Monoclonal or Polyclonal Monoclonal
Isotype IgG2a
Host Species Rat
Clone 1RNM44N

This 1RNM44N monoclonal antibody recognizes mouse CD170, also known as Siglec F. Siglec F is a cell surface lectin belonging to the Ig superfamily that binds glycoconjugates containing sialic acids that are commonly found on various cell types. The cytoplasmic domain of Siglec F contains an immunoreceptor tyrosine-based inhibitory motif (ITIM) that initiates intracellular signaling upon ligand binding. Siglec F is expressed mostly on eosinophils and alveolar macrophages and lower levels of this receptor have also been reported on immature myelomonocytic cells. Mouse Siglec F is a functional ortholog of human Siglec 8, however, unlike human Siglec 8, mouse Siglec F is not expressed on mast cells.

This 1RNM44N antibody will recognize a formaldehyde-fixed epitope.