CD170 (Siglec F) Rat, Alexa Fluor 700, Clone: 1RNM44N, eBioscience™

Rat Monoclonal Antibody

Overview
Brand: Affymetrix eBioscience

Manufacturer Part Number: 56-1702-80

Code: NEW

Additional Details:
Additional Details: Weight: 0.09500kg



Disclaimers: For Research Use Only.

Product Code. 15540357

Quantity Price
1 £ 66.65 / 25µg
EU Stock 4
Add to basket


Description and Specification

Specification

Isotype IgG2a
Formulation aqueous buffer, 0.09% sodium azide, may contain carrier protein/stabilizer
Quantity 25μg
Clone 1RNM44N
Antigen CD170 (Siglec F)
Conjugate Alexa Fluor 700
Regulatory Status RUO
Storage Requirements Store at 2-8°C. Do not freeze. Light-sensitive material.
Concentration 0.2mg/mL
Monoclonal or Polyclonal Monoclonal
Primary or Secondary Primary
Format Conjugated
Host Species Rat
Applications Flow Cytometry
Species Reactivity Mouse

This 1RNM44N monoclonal antibody recognizes mouse CD170, also known as Siglec F. Siglec F is a cell surface lectin belonging to the Ig superfamily that binds glycoconjugates containing sialic acids that are commonly found on various cell types. The cytoplasmic domain of Siglec F contains an immunoreceptor tyrosine-based inhibitory motif (ITIM) that initiates intracellular signaling upon ligand binding. Siglec F is expressed mostly on eosinophils and alveolar macrophages and lower levels of this receptor have also been reported on immature myelomonocytic cells. Mouse Siglec F is a functional ortholog of human Siglec 8, however, unlike human Siglec 8, mouse Siglec F is not expressed on mast cells.

This 1RNM44N antibody will recognize a formaldehyde-fixed epitope.