CD169 (Siglec-1) Mouse anti-Human, PE-eFluor 610, Clone: 7-239, eBioscience™

Mouse Monoclonal Antibody

Overview
Brand: Affymetrix eBioscience

Manufacturer Part Number: 61-1699-42

Code: NEW

Additional Details:
Additional Details: Weight: 0.23750kg



Disclaimers: For Research Use Only.

Product Code. 15580467

Quantity Price
1 £ 201.16 / 100 tests
Estimated Shipment date
from Supplier 04-05-2017
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Description and Specification

Specification

Species Reactivity Human
Formulation aqueous buffer, 0.09% sodium azide, may contain carrier protein/stabilizer
Isotype IgG1
Antigen CD169 (Siglec-1)
Clone 7-239
Regulatory Status RUO
Gene Alias Sialoadhesin
Quantity 100 tests
Host Species Mouse
Monoclonal or Polyclonal Monoclonal
Primary or Secondary Primary
Conjugate PE-eFluor 610
Storage Requirements Store at 2-8°C. Do not freeze. Light-sensitive material. This tandem dye is sensitive to photo-induced oxidation. Protect this vial from light during storage
Format Conjugated
Concentration 5μL (0.5μg)/test
Applications Flow Cytometry

This 7-239 monoclonal antibody reacts with human CD169, also known as Siglec-1 and Sialoadhesin. This type I transmembrane protein is a member of the sialic acid binding Ig-like lectin (Siglec) family. Expressed on macrophages and dendritic cells in peripheral blood, lymph nodes, and spleen in humans, CD169 binds glycoproteins and glycolipids containing N-acetylneuraminyl alpha 2-3-galactose. CD169 expression can also be induced on CD14+ monocytes by interferon-alpha and interferon-gamma to mediate HIV-1 infection. Finally, CD169 has also been shown to be involved in antigen presentation to invariant NK T cells.

This monoclonal antibody has been reported to inhibit erythrocyte binding to CD169-expressing cells.