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CD169 (Siglec-1) Mouse anti-Human, PE, Clone: 7-239, eBioscience™

Mouse Monoclonal Antibody

Brand:  Affymetrix eBioscience 12-1699-42

Code : NEW

Additional Details : Weight : 0.23750kg

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Product Code. 15506926

  • £182.82 / 100 tests


EU Stock 1
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Disclaimers:

For Research Use Only.


Specifications

Description

This 7-239 monoclonal antibody reacts with human CD169, also known as Siglec-1 and Sialoadhesin. This type I transmembrane protein is a member of the sialic acid binding Ig-like lectin (Siglec) family. Expressed on macrophages and dendritic cells in peripheral blood, lymph nodes, and spleen in humans, CD169 binds glycoproteins and glycolipids containing N-acetylneuraminyl alpha 2-3-galactose. CD169 expression can also be induced on CD14+ monocytes by interferon-alpha and interferon-gamma to mediate HIV-1 infection. Finally, CD169 has also been shown to be involved in antigen presentation to invariant NK T cells.

This monoclonal antibody has been reported to inhibit erythrocyte binding to CD169-expressing cells.
Description & Specifications

Specifications

CD169 (Siglec-1)
7-239
PE
Conjugated
Murine
100 Tests
Store at 2-8°C. Do not freeze. Light-sensitive material.
Monoclonal
Flow Cytometry
5μL (0.5μg)/test
aqueous buffer, 0.09% sodium azide, may contain carrier protein/stabilizer
Sialoadhesin
IgG1
RUO
Primary
Human