CD169 (Siglec-1) Mouse anti-Human, PE, Clone: 7-239, eBioscience™
Mouse Monoclonal Antibody
Brand: Affymetrix eBioscience 12-1699-42
Code : NEW
Additional Details : Weight : 0.23750kg
DescriptionThis 7-239 monoclonal antibody reacts with human CD169, also known as Siglec-1 and Sialoadhesin. This type I transmembrane protein is a member of the sialic acid binding Ig-like lectin (Siglec) family. Expressed on macrophages and dendritic cells in peripheral blood, lymph nodes, and spleen in humans, CD169 binds glycoproteins and glycolipids containing N-acetylneuraminyl alpha 2-3-galactose. CD169 expression can also be induced on CD14+ monocytes by interferon-alpha and interferon-gamma to mediate HIV-1 infection. Finally, CD169 has also been shown to be involved in antigen presentation to invariant NK T cells.
This monoclonal antibody has been reported to inhibit erythrocyte binding to CD169-expressing cells.
|Store at 2-8°C. Do not freeze. Light-sensitive material.|
|aqueous buffer, 0.09% sodium azide, may contain carrier protein/stabilizer|