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CD166 (ALCAM) Monoclonal Antibody (eBioALC48), FITC, eBioscience™, Invitrogen™
Rat Monoclonal Antibody
£175.00
Specifications
Antigen | CD166 (ALCAM) |
---|---|
Clone | eBioALC48 |
Concentration | 0.5 mg/mL |
Applications | Flow Cytometry |
Classification | Monoclonal |
Product Code | Brand | Quantity | Price | Quantity & Availability | |||||
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Product Code | Brand | Quantity | Price | Quantity & Availability | |||||
15536506
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Affymetrix eBioscience
11-1661-82 |
100 μg |
£175.00
100µg |
Estimated Shipment: 29-04-2024 Log in to see stock. |
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Description
Description: Activated leukocyte cell adhesion molecule (ALCAM; CD166) is a 105 kD cell-surface adhesion molecule belonging to the Ig superfamily of receptors. ALCAM is a type I transmembrane glycoprotein, possessing five extracellular Ig domains, a transmembrane domain, and a short cytoplasmic tail. ALCAM is involved in homotypic adhesion, as well as heterotypic adhesion with its natural ligand, CD6. A soluble isoform of ALCAM has been shown to inhibit homophilic adhesive interactions. ALCAM is expressed on a variety of cell types, including activated T and B cells, monocyte-derived dendritic cells, and thymic epithelial cells. ALCAM expression has also been used as a marker for the isolation of pluripotent stem cells. Applications Reported: This eBioALC48 antibody has been reported for use in flow cytometric analysis. Applications Tested: This eBioALC48 antibody has been tested by flow cytometric analysis of stimulated mouse splenocytes. This can be used at less than or equal to 0.5 μg per test. A test is defined as the amount (μg) of antibody that will stain a cell sample in a final volume of 100 μL. Cell number should be determined empirically but can range from 10^5 to 10^8 cells/test. It is recommended that the antibody be carefully titrated for optimal performance in the assay of interest. Excitation: 488 nm; Emission: 520 nm; Laser: Blue Laser. Filtration: 0.2 μm post-manufacturing filtered.
This gene encodes activated leukocyte cell adhesion molecule (ALCAM), also known as CD166 (cluster of differentiation 166), which is a member of a subfamily of immunoglobulin receptors with five immunoglobulin-like domains (VVC2C2C2) in the extracellular domain. This protein binds to T-cell differentiation antigene CD6, and is implicated in the processes of cell adhesion and migration. Multiple alternatively spliced transcript variants encoding different isoforms have been found.Specifications
CD166 (ALCAM) | |
0.5 mg/mL | |
Monoclonal | |
Liquid | |
RUO | |
Q61490 | |
IgG2a κ | |
Affinity chromatography | |
Antibody |
eBioALC48 | |
Flow Cytometry | |
FITC | |
Rat | |
Mouse | |
11658 | |
Primary | |
4° C, store in dark, DO NOT FREEZE! |
For Research Use Only.