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CD162 (PSGL-1) Mouse anti-Human, PerCP-eFluor 710, Clone: FLEG, eBioscience™

Mouse Monoclonal Antibody

Brand:  Affymetrix eBioscience 46-1629-42

Code : NEW

Additional Details : Weight : 0.23750kg

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Product Code. 15579196

  • £182.87 / 100 tests


Estimated Shipment date
from Supplier 31-07-2017
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Disclaimers:

For Research Use Only.


Specifications

Description

This FLEG monoclonal antibody recognizes human CD162, which is also known as P-selectin glyocoprotein ligand-1 (PSGL-1). This 120kDa protein exists as a homodimer on the surface of monocytes, neutrophils, granulocytes, peripheral T cells, some B cells, and a subset of CD34+ hematopoietic progenitor cells (HPCs) in the bone marrow. CD162 binds CD62P (P-selectin), CD62E (E-selectin), and CD62L (L-selectin) to mediate leukocyte interactions with each other as well as with activated platelets and endothelium. Thus, CD162 plays a critical role in leukocyte adhesion and rolling. Furthermore, the binding of CD162 to P-selectin on HPCs has been demonstrated to inhibit hematopoiesis. Studies have also demonstrated CD162 as the receptor for enterovirus 71.
Description & Specifications

Specifications

CD162 (PSGL-1)
FLEG
PerCP-eFluor 710
aqueous buffer, 0.09% sodium azide, may contain carrier protein/stabilizer
IgG2a
RUO
Primary
Human
Flow Cytometry
5μL (0.06μg)/test
Conjugated
Murine
100 Tests
Store at 2-8°C. Do not freeze. Light-sensitive material.
Monoclonal