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CD162 (PSGL-1) Mouse anti-Human, APC, Clone: FLEG, eBioscience™

Mouse Monoclonal Antibody

Brand:  Affymetrix eBioscience 17-1629-42

Code : NEW

Additional Details : Weight : 0.23750kg

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Product Code. 15598026

  • £213.39 / 100 tests


Estimated Shipment date
from Supplier 31-10-2017
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Disclaimers:

For Research Use Only.


Description

Description

This FLEG monoclonal antibody recognizes human CD162, which is also known as P-selectin glyocoprotein ligand-1 (PSGL-1). This 120kDa protein exists as a homodimer on the surface of monocytes, neutrophils, granulocytes, peripheral T cells, some B cells, and a subset of CD34+ hematopoietic progenitor cells (HPCs) in the bone marrow. CD162 binds CD62P (P-selectin), CD62E (E-selectin), and CD62L (L-selectin) to mediate leukocyte interactions with each other as well as with activated platelets and endothelium. Thus, CD162 plays a critical role in leukocyte adhesion and rolling. Furthermore, the binding of CD162 to P-selectin on HPCs has been demonstrated to inhibit hematopoiesis. Studies have also demonstrated CD162 as the receptor for enterovirus 71.
Specifications

Specifications

CD162
FLEG
APC
Conjugated
IgG2a
RUO
Primary
Human
Flow Cytometry
5μL (0.125μg)/test
aqueous buffer, 0.09% sodium azide, may contain carrier protein/stabilizer
Murine
100 Tests
Store at 2-8°C. Do not freeze. Light-sensitive material.
Monoclonal