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CD162 (PSGL-1), APC, clone: FLEG, eBioscience™

Mouse Monoclonal Antibody

Brand:  Affymetrix eBioscience 17-1629-42

Code : NEW

Additional Details : Weight : 0.23750kg

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Product Code. 15598026

  • £217.68 / 100 tests


EU Stock 15
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Description

Description

Description: This FLEG monoclonal antibody recognizes human CD162, which is also known as P-selectin glyocoprotein ligand-1 (PSGL-1). This 120-kDa protein exists as a homodimer on the surface of monocytes, neutrophils, granulocytes, peripheral T cells, some B cells, and a subset of CD34+ hematopoietic progenitor cells (HPCs) in the bone marrow. CD162 binds CD62P (P-selectin), CD62E (E-selectin), and CD62L (L-selectin) to mediate leukocyte interactions with each other as well as with activated platelets and endothelium. Thus, CD162 plays a critical role in leukocyte adhesion and rolling. Furthermore, the binding of CD162 to P-selectin on HPCs has been demonstrated to inhibit hematopoiesis. Studies have also demonstrated CD162 as the receptor for enterovirus 71.Applications Reported: This FLEG antibody has been reported for use in flow cytometric analysis.Applications Tested: This FLEG antibody has been pre-titrated and tested by flow cytometric analysis of normal human peripheral blood cells. This can be used at 5 μL (0.125 μg) per test. A test is defined as the amount (μg) of antibody that will stain a cell sample in a final volume of 100 μL. Cell number should be determined empirically but can range from 10^5 to 10^8 cells/test.Excitation: 633-647 nm; Emission: 660 nm; Laser: Red Laser.Filtration: 0.2μm post-manufacturing filtered.
Specifications

Specifications

CD162
Monoclonal
5μl/Test
PBS with 0.1% gelatin, 0.2% BSA and 0.09% sodium azide; pH 7.2
Q14242
CD162, CLA, cutaneous lymphocyte-associated associated antigen, P-Selectin Glycoprotein Ligand 1, PSGL1, SELPG
Murine
Affinity chromatography
RUO
Antibody
Monoclonal
Human
Flow Cytometry
FLEG
APC
SELPLG
Conjugated
SELPLG
IgG2a
100 Tests
Store at 2-8°C. Do not freeze. Light-sensitive material.
Primary
6404
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