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CD161 Monoclonal Antibody (HP-3G10), PE-eFluor™ 610, eBioscience™, Invitrogen™
Mouse Monoclonal Antibody
Brand: Affymetrix eBioscience 61-1619-42
185.34 GBP valid until 2024-03-29
Use promo code "21615" to get your promotional price.
Code : NEW
Additional Details : Weight : 0.23750kg
Description
Plays an inhibitory role on natural killer (NK) cells cytotoxicity. Activation results in specific acid sphingomyelinase/SMPD1 stimulation with subsequent marked elevation of intracellular ceramide. Activation also leads to AKT1/PKB and RPS6KA1/RSK1 kinases stimulation as well as markedly enhanced T-cell proliferation induced by anti-CD3. Acts as a lectin that binds to the terminal carbohydrate Gal-alpha(1,3)Gal epitope as well as to the N-acetyllactosamine epitope. Binds also to CLEC2D/LLT1 as a ligand and inhibits NK cell-mediated cytotoxicity as well as interferon-gamma secretion in target cells. {ECO:0000269; PubMed:16455998, ECO:0000269; PubMed:16925668, ECO:0000269; PubMed:8077657}.
CD161 Monoclonal antibody specifically detects CD161 in Human samples. It is validated for Flow Cytometry.Specifications
CD161 | |
Monoclonal | |
5 μL/Test | |
PBS with 0.2% BSA and 0.09% sodium azide; pH 7.2 | |
Q12918 | |
Klrb1 | |
Affinity chromatography | |
RUO | |
3820 | |
4° C, store in dark, DO NOT FREEZE! | |
Liquid |
Flow Cytometry | |
HP-3G10 | |
PE-eFluor 610 | |
Klrb1 | |
4930431A04Rik; Antigen 3.2.3; CD161; CD161 antigen-like family member A; CD161 antigen-like family member B; CD161a; CD161b; CLEC5B; C-type lectin domain family 5 member B; EMBL:AAQ11375.1}; Gm4696; HNKR-P1a; Immunoreceptor NKR-P1E; immunoreceptor NKR-P1G; inhibitory receptor NKR-P1B; killer cell lectin like receptor B1; killer cell lectin-like receptor subfamily A member 1 complex; killer cell lectin-like receptor subfamily B member 1; killer cell lectin-like receptor subfamily B member 1 complex; killer cell lectin-like receptor subfamily B member 1A; killer cell lectin-like receptor subfamily B member 1B; killer cell lectin-like receptor subfamily B member 1B allele A; Killer cell lectin-like receptor subfamily B member 1B allele B; killer cell lectin-like receptor subfamily B member 1B allele C; killer cell lectin-like receptor subfamily B member 1D; killer cell lectin-like receptor subfamily B member 1F; killer cell lectin-like receptor subfamily B member 1G; killer cell lectin-li | |
Mouse | |
100 Tests | |
Primary | |
Human | |
Antibody | |
IgG1 κ |
For Research Use Only.