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CD161 Mouse anti-Human, PE-Cy7, Clone: HP-3G10, eBioscience™

Mouse Monoclonal Antibody

Brand:  Affymetrix eBioscience 25-1619-42

Code : NEW

Additional Details : Weight : 0.23750kg

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Product Code. 15598496

  • £205.24 / 100 tests


EU Stock 3
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Disclaimers:

For Research Use Only.


Description

Description

This HP-3G10 monoclonal antibody reacts with CD161 (also known as NKR-P1A), a member of the C-type lectin superfamily. The human homologue of NK1.1 in C57BL/6 mice, CD161 is expressed on natural killer cells and is upregulated in response to IL-12. CD161 can also be detected on various T cell subsets, including memory/effector CD4+ T cells, CD8+ T cells, gamma delta TCR T cells, and a subset of CD3+ thymocytes. Finally, CD161 expression has been demonstrated on human Th17 CD4+ T cells. The function of this receptor is unclear although studies suggest a possible stimulatory role. Nevertheless, Lectin-like transcript-1 (LLT1), which is also known as osteoclast inhibitory lectin, has been identified as the ligand for CD161.
Specifications

Specifications

CD161
HP-3G10
PE-Cy7
Conjugated
Murine
100 Tests
Store at 2-8°C. Do not freeze. Light-sensitive material. This tandem dye is sensitive to photo-induced oxidation. Protect this vial from light during storage
Monoclonal
Flow Cytometry
5μL (0.25μg)/test
aqueous buffer, 0.09% sodium azide, may contain carrier protein/stabilizer
NKR-P1A, NKRP1A
IgG1
RUO
Primary
Human