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CD161 Mouse anti-Human, eFluor® 450, Clone: HP-3G10, eBioscience™

Mouse Monoclonal Antibody

£80.00 - £200.00

Specifications

Antigen CD161
Clone HP-3G10
Target Species Human
Conjugate eFluor™ 450
Isotype IgG1, kappa
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Products 2
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Product Code Brand Quantity Price Quantity & Availability  
15589726
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Affymetrix eBioscience
48-1619-41
25 Tests £80.00
25 tests View alternative products
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Estimated Shipment
30-11-2020
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15599726
View Documents
Affymetrix eBioscience
48-1619-42
100 Tests £200.00
100 tests View alternative products
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Description

Description

Excitation: 405 nm; Emission: 445 nm; Laser: Violet Laser. Filtration: 0.2 μm post-manufacturing filtered. Plays an inhibitory role on natural killer (NK) cells cytotoxicity. Activation results in specific acid sphingomyelinase/SMPD1 stimulation with subsequent marked elevation of intracellular ceramide. Activation also leads to AKT1/PKB and RPS6KA1/RSK1 kinases stimulation as well as markedly enhanced T-cell proliferation induced by anti-CD3. Acts as a lectin that binds to the terminal carbohydrate Gal-alpha(1,3)Gal epitope as well as to the N-acetyllactosamine epitope. Binds also to CLEC2D/LLT1 as a ligand and inhibits NK cell-mediated cytotoxicity as well as interferon-gamma secretion in target cells. {ECO:0000269; PubMed:16455998, ECO:0000269; PubMed:16925668, ECO:0000269; PubMed:8077657}.
Specifications

Specifications

CD161
Human
IgG1, kappa
Monoclonal
Liquid
Antibody
4° C, store in dark, DO NOT FREEZE!
HP-3G10
eFluor™ 450
Flow Cytometry
Primary
Monoclonal
PBS with 0.1% gelatin, 0.2% BSA and 0.09% sodium azide; pH 7.2
RUO

For Research Use Only.