CD161 Mouse anti-Human, eFluor 450, Clone: HP-3G10, eBioscience™

Mouse Monoclonal Antibody

Overview
Brand: Affymetrix eBioscience

Manufacturer Part Number: 48-1619-41

Code: NEW

Additional Details:
Additional Details: Weight: 0.23750kg



Disclaimers: For Research Use Only.

Product Code. 15589726

Quantity Price
1 £ 74.51 / 25 tests
Estimated Shipment date
from Supplier 05-05-2017
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Description and Specification

Specification

Host Species Murine
Quantity 25 Tests
Primary or Secondary Primary
Concentration 5μL (0.25μg)/test
Format Conjugated
Monoclonal or Polyclonal Monoclonal
Formulation aqueous buffer, 0.09% sodium azide, may contain carrier protein/stabilizer
Conjugate eFluor 450
Isotype IgG1
Applications Flow Cytometry
Gene Alias NKRP1A
Species Reactivity Human
Clone HP-3G10
Regulatory Status RUO
Antigen CD161
Storage Requirements Store at 2-8°C. Do not freeze. Light-sensitive material.

This HP-3G10 monoclonal antibody reacts with CD161 (also known as NKR-P1A), a member of the C-type lectin superfamily. The human homologue of NK1.1 in C57BL/6 mice, CD161 is expressed on natural killer cells and is upregulated in response to IL-12. CD161 can also be detected on various T cell subsets, including memory/effector CD4+ T cells, CD8+ T cells, gamma delta TCR T cells, and a subset of CD3+ thymocytes. Finally, CD161 expression has been demonstrated on human Th17 CD4+ T cells. The function of this receptor is unclear although studies suggest a possible stimulatory role. Nevertheless, Lectin-like transcript-1 (LLT1), which is also known as osteoclast inhibitory lectin, has been identified as the ligand for CD161.