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CD161 Mouse anti-Human, eFluor® 450, Clone: HP-3G10, eBioscience™

Mouse Monoclonal Antibody

Brand:  Affymetrix eBioscience 48-1619-41

Code : NEW

Additional Details : Weight : 0.23750kg

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Product Code. 15589726

  • £80.00 / 25 tests

Estimated Shipment date
from Supplier 24-03-2020

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Description

Description

Excitation: 405 nm; Emission: 445 nm; Laser: Violet Laser. Filtration: 0.2 μm post-manufacturing filtered. Plays an inhibitory role on natural killer (NK) cells cytotoxicity. Activation results in specific acid sphingomyelinase/SMPD1 stimulation with subsequent marked elevation of intracellular ceramide. Activation also leads to AKT1/PKB and RPS6KA1/RSK1 kinases stimulation as well as markedly enhanced T-cell proliferation induced by anti-CD3. Acts as a lectin that binds to the terminal carbohydrate Gal-alpha(1,3)Gal epitope as well as to the N-acetyllactosamine epitope. Binds also to CLEC2D/LLT1 as a ligand and inhibits NK cell-mediated cytotoxicity as well as interferon-gamma secretion in target cells. {ECO:0000269; PubMed:16455998, ECO:0000269; PubMed:16925668, ECO:0000269; PubMed:8077657}.
Specifications

Specifications

CD161
Monoclonal
5 μL/Test
PBS with 0.1% gelatin, 0.2% BSA and 0.09% sodium azide; pH 7.2
Q12918
Ly55a, NKR-P1A, NKRP12, Nkrp1-a, Nkrp1a
Mouse
Affinity chromatography
RUO
Antibody
Monoclonal
Human
Flow Cytometry
HP-3G10
eFluor™ 450
KLRB1
Liquid
KLRB1
IgG1, kappa
25 Tests
4° C, store in dark, DO NOT FREEZE!
Primary
3820
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For Research Use Only.