CD16 Mouse anti-Human, PE, Clone: B73.1, eBioscience™

Mouse Monoclonal Antibody

Overview
Brand: Affymetrix eBioscience

Manufacturer Part Number: 12-0167-41

UNSPSC: 12352203

Code: Z2

Additional Details:
Additional Details: Weight: 0.50000kg



Disclaimers: For Research Use Only.

Product Code. 13166784

Quantity Price
1 £ 60.53 / Each
EU Stock 3
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Description and Specification

Specification

Host Species Murine
Quantity 25 Tests
Isotype IgG1
Species Reactivity Human
Regulatory Status RUO
Concentration 5μL (0.5μg)/test
Antigen CD16
Gene Alias Low Affinity IgG Receptor 3, FCGR3a, FCGR3, IGFR3
Applications Flow Cytometry
Primary or Secondary Primary
Formulation aqueous buffer, 0.09% sodium azide, may contain carrier protein/stabilizer
Storage Requirements Store at 2-8°C. Do not freeze. Light-sensitive material.
Format Conjugated
Clone B73.1
Monoclonal or Polyclonal Monoclonal
Conjugate PE

This B73.1 monoclonal antibody reacts with human CD16, a member of the Fc receptor family also known as Fc gamma RIIIa and Fc gamma RIIIb. This 50-65kDa receptor is expressed on natural killer cells, neutrophils, monocytes, and macrophages. Crosslinking of CD16 in natural killer cells and monocytes results in activation of the MAPK and PI3K signaling pathways, thus regulating the production of TNF alpha, IL-6, and IL-1 beta.

This monoclonal antibody has been shown to block Fc receptor functions.